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- Table of Contents
Facts about Phosphoglucomutase-like protein 5.
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Human | |
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Gene Name: | PGM5 |
Uniprot: | Q15124 |
Entrez: | 5239 |
Belongs to: |
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phosphohexose mutase family |
aciculin; EC 5.4.2.2; PGM-RP; PGMRPphosphoglucomutase-like protein 5; phosphoglucomutase 5; Phosphoglucomutase-related protein
Mass (kDA):
62.225 kDA
Human | |
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Location: | 9q21.11 |
Sequence: | 9; NC_000009.12 (68356584..68531061) |
Detected in smooth and cardiac muscle at high levels and in skeletal muscle at low level. Present in other tissues due to vascular or other smooth muscle component. Low levels are present in liver, kidney, skin and brain (at protein level).
Cell junction, adherens junction. Cytoplasm, cytoskeleton. Adherens-type cellular junctions. Concentrated in focal contacts at the ends of actin bundles, and associated with actin filaments.
PMID: 9342213 by Moiseeva E.P., et al. Characterisation of the promoter which regulates expression of a phosphoglucomutase-related protein, a component of the dystrophin/utrophin cytoskeleton predominantly expressed in smooth muscle.
PMID: 8631316 by Moiseeva E.P., et al. A novel dystrophin/utrophin-associated protein is an enzymatically inactive member of the phosphoglucomutase superfamily.