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Placenta growth factor Antibodies
AND PGF ELISA kits, Placenta growth factor Proteins
Many biological assays use antibodies to detect Placenta growth factor, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Placenta growth factor in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Placenta growth factor antibodies...
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PGF Infographic by Boster Bio
All PGF Products
Product
Figures
Specificity
Applications
Price
Human PLGF/PGF ELISA Kit PicoKine®
5 Citations 11 Q&As
Human
ELISA
$499
Cat # EK0490
96 wells/kit, with removable strips.
Cat # EK0490
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK0863
96 wells/kit, with removable strips.
Cat # EK0863
96 wells/kit, with removable strips.
Human
$250
Cat # PROTP49763
2ug, 10ug, 1mg
Cat # PROTP49763
2ug, 10ug, 1mg
PGF Overview
Facts about Placenta growth factor.
Placenta growth factor (PGF)
Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1.
Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 at a heparin-dependent Method. Also promotes cell tumor development.
Gene Information
| Human | |
|---|---|
| Gene Name: | PGF |
| Uniprot: | P49763 |
| Entrez: | 5228 |
Family
| Belongs to: |
|---|
| PDGF/VEGF growth factor family |
Alternative Names
D12S1900; PGF; PGFL; placenta growth factor; placental growth factor; placental growth factor, vascular endothelial growth factor-related protein; PlGF; PlGF-2; PLGFplacental growth factor-like; SHGC-10760
Molecular Weight
Mass (kDA):
24.789 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 14q24.3 |
| Sequence: | 14; NC_000014.9 (74941830..74955764, complement) |
Tissue Specificity
While the three isoforms are present in most placental tissues, PlGF-2 is specific to early (8 week) placenta and only PlGF-1 is found in the colon and mammary carcinomas.
Subcellular Localizations
Secreted. The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin.
Diseases
- Endometrial Polyp
- Inflammation
- Pathologic Vasoconstriction
- Hypertensive Disease
- Mycoplasma Pneumonia
- Malignant Neoplasms
- Neoplasms
- Pituitary Diseases
- Cattle Diseases
- Diabetes Mellitus
- Hypoxia
- Polyendocrinopathies, Autoimmune
- Premature Obstetric Labor
Interacting Proteins
- FLT1
Pathways
- Estrus
- Ovulation
- Secretion
- Luteolysis
- Insemination
- Parturition
- Excretion
- Transport
- Pathogenesis
- Vasoconstriction
- Diestrus
- Angiogenesis
- Progesterone Secretion
PTMs
- Phosphorylation
- Oxidation
- Cleavage
- Reduction
- Dephosphorylation
- Nitration
- Glycosylation
Research Areas
- Angiogenesis
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PGF
bosterbio.com/bosterbio-gene-info-cards/PGF
References
PMID: 1924389 by Maglione D., et al. Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor.
PMID: 8148155 by Hauser S.D., et al. A heparin-binding form of placenta growth factor (PlGF-2) is expressed in human umbilical vein endothelial cells and in placenta.
6 Publications of Boster Placenta growth factor Antibodies & ELISA Kits
- PubMed ID: 10.3109/10641955.2015.1122035, Attenuation of hyperglycemia-induced apoptotic signaling and anti-angiogenic mil...
- PubMed ID: 10.1038/s41419-017-0258-2, miR-143-3p targeting of ITGA6 suppresses tumour growth and angiogenesis by downr...
- PubMed ID: 10.1007/s13300-018-0527-9, Concentrations of VEGF and PlGF Decrease in Eyes After Intravitreal Conbercept I...
- PubMed ID: -, Liu M,Wang RB,Xing JH,Tang YX.Nested Case–Control Study of Corin Combined with...
- PubMed ID: 27936076, Ratajczak J, Hilkens P, Gervois P, Wolfs E, Jacobs R, Lambrichts I, Bronckaers A...
- PubMed ID: 22079325, Xu Y, Luo J, Yue Z, Wu L, Zhang X, Zhou C, Zhao F, Wang X, Chen G. Brain Res. 20...
*More publications can be found for each product on its corresponding product page