PEX6 Antibodies

AND PEX6 ELISA kits, PEX6 Proteins

Many biological assays use antibodies to detect PEX6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PEX6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PEX6 antibodies...

We validate the specificity of these antibodies to PEX6 by testing them on tissues known to express PEX6 positively and negatively. Browse below to find the PEX6 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PEX6 Infographic by Boster Bio

All PEX6 Products

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Anti-Peroxisome assembly factor 2 PEX6 Antibody

Human, Mouse, Rat

$405
Cat # A04353
100ul

PEX6 (NM_000287) Human Recombinant Protein

$1062
Cat # PROTQ13608
20 µg

PEX6 Overview

Facts about Peroxisome assembly factor 2.

PEX6 3D structure. Source: alphafold

Peroxisome assembly factor 2 (PEX6)

Involved in peroxisome biosynthesis. Required for stability of the PTS1 receptor.

Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes. .

Gene Information

Human
Gene Name:	PEX6
Uniprot:	Q13608
Entrez:	5190

Family

Belongs to:

AAA ATPase family

Alternative Names

PAF2; PAF-2peroxisome assembly factor 2; Peroxin-6; peroxisomal biogenesis factor 6peroxin-6; Peroxisomal-type ATPase 1; peroxisome biogenesis factor 6; PXAAA1peroxisomal AAA-type ATPase 1

Molecular Weight

Mass (kDA):
104.061 kDA

Genomic Context


Human

Location:	6p21.1
Sequence:	6; NC_000006.12 (42963865..42980224, complement)

Tissue Specificity

Expressed in the retina, at higher levels in the photoreceptor layer at the joint between the outer and inner segments.

Subcellular Localizations

Cytoplasm. Peroxisome membrane. Cell projection, cilium, photoreceptor outer segment. Associated with peroxisomal membranes. Localized at the base of the outer segment of photoreceptor cells (PubMed:26593283).

Diseases

Aortic Aneurysm, Abdominal
Zellweger Syndrome
Disorders Of Peroxisome Biogenesis
Peroxisomal Disorders
Adrenoleukodystrophy
Adrenoleukodystrophy, Neonatal
Infantile Refsum Disease (disorder)
Refsum Disease
Chondrodysplasia Punctata
Abnormal Degeneration
Hepatomegaly
Embryonic Mosaic

Dislocations
Malnutrition
Mitochondrial Diseases
Neuronal Migration Disorders
Fibrosis
Malignant Neoplasms

Interacting Proteins

PEX1

Pathways

Protein Import
Localization
Transport
Virulence
Translation
Fatty Acid Beta-oxidation
Pathogenesis
Rna Interference
Glyoxylate Cycle
Protein Secretion
Cell Cycle
Glycosylation
Protein Transport

Cell Death
Necrotic Cell Death
Germination
Photorespiration
Secretion
Seedling Development
Developmental Process

PTMs

Ubiquitination
Oxidation

Glycosylation
Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PEX6

References

PMID: 8670792 by Yahraus T., et al. The peroxisome biogenesis disorder group 4 gene, PXAAA1, encodes a cytoplasmic ATPase required for stability of the PTS1 receptor.

PMID: 8940266 by Fukuda S., et al. Human peroxisome assembly factor-2 (PAF-2): a gene responsible for group C peroxisome biogenesis disorder in humans.