Pescadillo homolog Antibodies

AND PES1 ELISA kits, Pescadillo homolog Proteins

Many biological assays use antibodies to detect Pescadillo homolog, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Pescadillo homolog in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Pescadillo homolog antibodies...

We validate the specificity of these antibodies to Pescadillo homolog by testing them on tissues known to express PES1 positively and negatively. Browse below to find the PES1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PES1 Infographic by Boster Bio

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Pescadillo (PES1) (NM_014303) Human Over-expression Lysate

Human

$628
Cat # LS023481
100 µg

PES1 Overview

Facts about Pescadillo homolog.

PES1 3D structure. Source: alphafold

Pescadillo homolog (PES1)

Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.

Gene Information

Human
Gene Name:	PES1
Uniprot:	O00541
Entrez:	23481

Family

Belongs to:

pescadillo family

Alternative Names

pescadillo homolog 1, containing BRCT domain (zebrafish); pescadillo homolog; PESpescadillo (zebrafish) homolog 1, containing BRCT domain

Molecular Weight

Mass (kDA):
68.003 kDA

Genomic Context


Human

Location:	22q12.2
Sequence:	22; NC_000022.11 (30576625..30607013, complement)

Tissue Specificity

Significant levels are detected in a variety of cancer cell lines, including glioblastoma, breast carcinoma, colon carcinoma and cervical carcinoma cells. Levels are abnormally elevated in malignant tumors of astrocytic origin.

Subcellular Localizations

Nucleus, nucleolus. Nucleus, nucleoplasm. Chromosome. Appears to localize to the periphery of metaphase chromosomes during mitosis and to the prenucleolar bodies that form in mitotic cells prior to the actual nucleoli.

Diseases

Malignant Neoplasms
Neoplasms
Cell Transformation, Neoplastic
Malignant Neoplasm Of Breast
Mammary Neoplasms
Candidiasis
Malignant Tumor Of Colon
Infective Disorder
Tumor Progression
Sleep Apnea, Obstructive
Sleep Apnea Syndromes

Malignant Neoplasm Of Lung
Carcinogenesis
Carcinoma
Disseminated Candidiasis
Myeloid Leukemia
Renal Cell Carcinoma

Interacting Proteins

BOP1
FOXM1
WDR12

Pathways

Cell Proliferation
Ribosome Biogenesis
Cell Cycle
Virulence
Localization
Cell Cycle Arrest
Rrna Processing
Dna Replication
Rna Interference
Transport
Cell Migration
Hyphal Growth
Protein Targeting

Brain Development
Regulation Of Gene Expression
Chromosome Segregation
Liver Development
Anaphase
Pronephros Development
Phagocytosis

PTMs

Prenylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PES1

References

PMID: 8985183 by Allende M.L., et al. Insertional mutagenesis in zebrafish identifies two novel genes, pescadillo and dead eye, essential for embryonic development.

PMID: 11071894 by Kinoshita Y., et al. Pescadillo, a novel cell cycle regulatory protein abnormally expressed in malignant cells.