PDLIM5 Antibodies

AND PDLIM5 ELISA kits, PDLIM5 Proteins

Many biological assays use antibodies to detect PDLIM5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDLIM5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDLIM5 antibodies...

We validate the specificity of these antibodies to PDLIM5 by testing them on tissues known to express PDLIM5 positively and negatively. Browse below to find the PDLIM5 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PDLIM5 Infographic by Boster Bio

All PDLIM5 Products

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Product

Figures

Specificity

Applications

Price

Anti-PDZ and LIM domain protein 5 PDLIM5 Antibody

Human, Mouse, Rat

$405
Cat # A03763
100ul

Anti-Phospho-PDLIM5 (Y251) Antibody

Human

ELISA, WB

$380
Cat # A03763Y251-1
100ul

Anti-PDLIM5 Mouse Monoclonal Antibody [Clone ID: OTI1A11]

Human, Mouse, Rat

Flow Cytometry, WB

$523
Cat # M03763
100 µl

PDLIM5 (NM_006457) Human Over-expression Lysate

Human

$628
Cat # LS010611
100 µg

PDLIM5 Overview

Facts about PDZ and LIM domain protein 5.

PDLIM5 3D structure. Source: alphafold

PDZ and LIM domain protein 5 (PDLIM5)

May play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion.

Overexpression promotes the development of heart hypertrophy. Contributes to the regulation of dendritic spine morphogenesis in neurons.

Gene Information

Human
Gene Name:	PDLIM5
Uniprot:	Q96HC4
Entrez:	10611

Family

Belongs to:

No superfamily

Alternative Names

Enh; ENH1; ENHLIM; Enigma homolog; enigma-like LIM domain protein; Enigma-like PDZ and LIM domains protein; PDZ and LIM domain 5; PDZ and LIM domain protein 5

Molecular Weight

Mass (kDA):
63.945 kDA

Genomic Context


Human

Location:	4q22.3
Sequence:	4; NC_000004.12 (94451857..94668227)

Subcellular Localizations

Cell junction, synapse, postsynaptic density. Cell junction, synapse, presynapse. Cell junction, synapse, postsynapse. Cytoplasm, cytosol. Detected both at presynaptic and postsynaptic sites, exclusively at excitatory synapses, but not inhibitory synapses, in hippocampal neurons.

Diseases

Bipolar Disorder
Schizophrenia
Depressive Disorder
Neoplasms
Malignant Neoplasms
Major Depressive Disorder
Mental Disorders
Carcinoma
Endoplasmic Reticulum Stress
Dysequilibrium Syndrome
Mood Disorders
Cell Transformation, Neoplastic

Fracture Of First Cervical Vertebra
Polyneuropathy
Malignant Neoplasm Of Breast
Mouth Neoplasms
Dysplasia
Neoplasms, Hormone-dependent
5,10-methylenetetrahydrofolate Reductase Deficiency

Interacting Proteins

COIL
ID2
KRT40
KRTAP10-7
ZYX

Pathways

Translation
Organ Development
Rna Interference
Gastrulation
Circadian Rhythm
Cell Cycle
Cell Death
Immune Response

Heart Development
Pathogenesis
Myoblast Differentiation

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PDLIM5

References

PMID: 10429367 by Ueki N., et al. Isolation, tissue expression, and chromosomal assignment of a human LIM protein gene, showing homology to rat enigma homologue (ENH).

PMID: 15346770 by Wu M., et al. Cloning and identification of a novel human gene PDLIM5, a homolog of AD-associated neuronal thread protein (AD7c-NTP).