PDLIM1 Antibodies

AND PDLIM1 ELISA kits, PDLIM1 Proteins

Many biological assays use antibodies to detect PDLIM1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDLIM1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDLIM1 antibodies...

We validate the specificity of these antibodies to PDLIM1 by testing them on tissues known to express PDLIM1 positively and negatively. Browse below to find the PDLIM1 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PDLIM1 Infographic by Boster Bio

All PDLIM1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-PDLIM1/Clim1 Antibody

13 Q&As

Human, Mouse, Rat

IF, IHC, WB

$360
Cat # A04832-1
100 µl

PDLIM1 Colorimetric Cell-Based ELISA

Human, Mouse, Rat

ELISA

$480
Cat # EKC1616
1 kit, containing one 96-well plate and all necessary reagents

PDLIM1 (NM_020992) Human Recombinant Protein

$1249
Cat # PROTO00151
20 µg

Anti-PDLIM1 Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, IP, IF, ICC, WB

$370
Cat # M04832
100 μl/vial

Anti-PDLIM1 Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, IF, ICC, WB

$370
Cat # M04832-1
100 μl/vial

PDLIM1 (NM_020992) Human Over-expression Lysate

Human

$628
Cat # LS009124
100 µg

PDLIM1 Overview

Facts about PDZ and LIM domain protein 1.

PDLIM1 3D structure. Source: alphafold

PDZ and LIM domain protein 1 (PDLIM1)

Cytoskeletal protein that may serve as an adapter that brings other proteins (like kinases) to the cytoskeleton (PubMed:10861853). Involved in assembly, disassembly and directioning of stress fibers in fibroblasts.

Required for the localization of ACTN1 and PALLD to stress fibers. Required for cell migration and in maintaining cell polarity of fibroblasts (By similarity).

Gene Information

Human
Gene Name:	PDLIM1
Uniprot:	O00151
Entrez:	9124

Family

Belongs to:

No superfamily

Alternative Names

CLIM1carboxyl terminal LIM domain protein 1; CLP-36; CLP36carboxy terminal LIM domain protein 1; C-terminal LIM domain protein 1; elfin; enigma; hCLIM1; LIM domain protein CLP-36; PDZ and LIM domain 1 (elfin); PDZ and LIM domain 1; PDZ and LIM domain protein 1

Molecular Weight

Mass (kDA):
36.072 kDA

Genomic Context


Human

Location:	10q23.33
Sequence:	10; NC_000010.11 (95237569..95291006, complement)

Tissue Specificity

Strongly expressed in the heart and skeletal muscle, moderately expressed in the spleen, small intestine, colon, placenta, and lung. A lower level expression is seen in liver, thymus, kidney, prostate and pancreas and is not found in the brain, testis, ovary, and peripheral blood leukocytes.

Subcellular Localizations

Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line. Associates with actin stress fibers.

Diseases

Nervousness
Tissue Adhesions
Acquired Immunodeficiency Syndrome
Dizziness
Hypoxia
Myeloid Leukemia, Chronic
Protein Deficiency
Myxoid Cyst
Myopathy
Segmental Glomerulosclerosis
Myeloid Leukemia
Headache
Pain

Adenocarcinoma
Pneumocystis Infections
Intraocular Pressure Disorder
Focal Glomerulosclerosis
Atrophy
Glaucoma
Dystrophy

Pathways

Localization
Cytoskeleton Organization
Cell Death
Transport
Proteolysis
Protein Oxidation
Immune Response
Platelet Activation
Autolysis
Humoral Immune Response
Inflammatory Response
Regeneration

Decidualization
Phagocytosis
Organ Development
Pathogenesis
Rna Interference
Focal Adhesion Assembly
Oncogenesis

PTMs

Phosphorylation

Cleavage

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PDLIM1

References

PMID: 10022510 by Kotaka M., et al. Characterization of the human 36-kDa carboxyl terminal LIM domain protein (hCLIM1).

PMID: 11110697 by Bauer K., et al. Human CLP-36, a PDZ-domain and LIM-domain protein, binds to alpha- actinin-1 and associates with actin filaments and stress fibers in activated platelets and endothelial cells.