PDHA2 Antibodies

AND PDHA2 ELISA kits, PDHA2 Proteins

Many biological assays use antibodies to detect PDHA2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDHA2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDHA2 antibodies...

We validate the specificity of these antibodies to PDHA2 by testing them on tissues known to express PDHA2 positively and negatively. Browse below to find the PDHA2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PDHA2 Infographic by Boster Bio

All PDHA2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-PDHA2 Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A11347
100ul

PDHA2 (NM_005390) Human Over-expression Lysate

Human

$628
Cat # LS005161
100 µg

PDHA2 Overview

Facts about Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial.

PDHA2 3D structure. Source: alphafold

Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial (PDHA2)

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. .

Gene Information

Human
Gene Name:	PDHA2
Uniprot:	P29803
Entrez:	5161

Family

Belongs to:

No superfamily

Alternative Names

EC 1.2.4.1; MGC149517; MGC149518; mitochondrial; PDHAL; PDHE1-A type II; pyruvate dehydrogenase (lipoamide) alpha 2; pyruvate dehydrogenase E1 component subunit alpha, testis-specific form; pyruvate dehydrogenase, E1-alpha polypeptide, testis specific

Molecular Weight

Mass (kDA):
42.933 kDA

Genomic Context


Human

Location:	4q22.3
Sequence:	4; NC_000004.12 (95840093..95841464)

Tissue Specificity

Testis. Expressed in postmeiotic spermatogenic cells.

Subcellular Localizations

Mitochondrion matrix.

Diseases

Haploinsufficiency
Obesity
Obesity, Morbid
Chromosome Breakage
Chromosomal Translocation

Pathways

Methylation
Acrosome Reaction
Sperm Capacitation
Spermatogenesis
Demethylation
Fertilization
Cell Differentiation
Dna Methylation

Ovulation
Localization

PTMs

Phosphorylation

Demethylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PDHA2

References

PMID: 2249846 by Dahl H.-H.M., et al. A testis-specific form of the human pyruvate dehydrogenase E1 alpha subunit is coded for by an intronless gene on chromosome 4.

PMID: 14638692 by Hiromasa Y., et al. Organization of the cores of the mammalian pyruvate dehydrogenase complex formed by E2 and E2 plus the E3-binding protein and their capacities to bind the E1 and E3 components.