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PDGFA Antibodies
AND PDGFA ELISA kits, PDGFA Proteins
Many biological assays use antibodies to detect PDGFA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDGFA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDGFA antibodies...
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PDGFA Infographic by Boster Bio
All PDGFA Products
Product
Figures
Specificity
Applications
Price
Mouse
$250
Cat # PROTP20033
2ug, 10ug, 1mg
Cat # PROTP20033
2ug, 10ug, 1mg
Human
$250
Cat # PROTP28576
2ug, 10ug, 1mg
Cat # PROTP28576
2ug, 10ug, 1mg
Anti-PDGF AA/PDGFA Antibody Picoband®
2 Citations
Human, Mouse, Rat
ELISA, IF, ICC, WB
$370
Cat # A02257-1
100 μg/vial
Cat # A02257-1
100 μg/vial
PDGFA Overview
Facts about Platelet-derived growth factor subunit A.
Platelet-derived growth factor subunit A (PDGFA)
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin.
Required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis. Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum.
Gene Information
| Human | |
|---|---|
| Gene Name: | PDGFA |
| Uniprot: | P04085 |
| Entrez: | 5154 |
Family
| Belongs to: |
|---|
| PDGF/VEGF growth factor family |
Alternative Names
PDGFAA; PDGF-AA
Molecular Weight
Mass (kDA):
24.043 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7p22.3 |
| Sequence: | 7; NC_000007.14 (497245..520668, complement) |
Subcellular Localizations
Secreted. Released by platelets upon wounding.
Diseases
- Neoplasms
- Malignant Neoplasms
- Malignant Paraganglionic Neoplasm
- Tissue Adhesions
- Carcinoma
- Fibrosis
- Tumor Angiogenesis
- Neoplasm Metastasis
- Inflammation
- Cell Transformation, Neoplastic
- Cytogenetic Abnormality
- Cell Invasion
Interacting Proteins
- PDGFRA
Pathways
- Localization
- Angiogenesis
- Pathogenesis
- Cell Proliferation
- Cell Migration
- Lung Development
- Cell Cycle
- Cell Growth
- Cell Adhesion
- Developmental Process
- Translation
- Wound Healing
- Oncogenesis
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PDGFA
bosterbio.com/bosterbio-gene-info-cards/PDGFA
References
PMID: 3422746 by Bonthron D.T., et al. Platelet-derived growth factor A chain: gene structure, chromosomal location, and basis for alternative mRNA splicing.
PMID: 2832727 by Rorsman F., et al. Structural characterization of the human platelet-derived growth factor A-chain cDNA and gene: alternative exon usage predicts two different precursor proteins.
2 Publications of Boster PDGFA Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.transproceed.2015.05.014, Effects of Monocyte Chemotactic Protein-1 and Nuclear Factor of Kappa B Pathway ...
- PubMed ID: 10.1016/j.jsps.2017.04.024, The effects of low-molecular-weight heparin on lung and pulmonary artery injurie...
*More publications can be found for each product on its corresponding product page