PDCD6IP Antibodies

AND PDCD6IP ELISA kits, PDCD6IP Proteins

Many biological assays use antibodies to detect PDCD6IP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDCD6IP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDCD6IP antibodies...

We validate the specificity of these antibodies to PDCD6IP by testing them on tissues known to express PDCD6IP positively and negatively. Browse below to find the PDCD6IP antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PDCD6IP Infographic by Boster Bio

All PDCD6IP Products

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Product

Figures

Specificity

Applications

Price

Anti-ALIX/PDCD6IP Antibody Picoband®

1 Citations 16 Q&As

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # PB9770
100 μg/vial

Anti-ALIX Rabbit Monoclonal Antibody

4 Q&As

Human, Mouse, Rat

Flow Cytometry, WB

$370
Cat # M01751
100 μl

Anti-ALIX/PDCD6IP Antibody Picoband®(monoclonal, 14D10)

1 Citations 5 Q&As

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M01751-1
100 μg/vial

Human Alix Recombinant Protein

SDS-PAGE

$243
Cat # PROTQ8WUM4
Starting from 20ug

PDCD6IP Overview

Facts about Programmed cell death 6-interacting protein.

PDCD6IP 3D structure. Source: alphafold

Programmed cell death 6-interacting protein (PDCD6IP)

Multifunctional protein involved in endocytosis, multivesicular body biogenesis, membrane repair, cytokinesis, apoptosis and maintenance of tight junction integrity. Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome.

Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway requires the sequential function of ESCRT-O, -I,-II and -III complexes (PubMed:14739459).

Gene Information

Human
Gene Name:	PDCD6IP
Uniprot:	Q8WUM4
Entrez:	10015

Family

Belongs to:

No superfamily

Alternative Names

AIP1DRIP4; ALG-2 interacting protein 1; ALG-2 interacting protein X; ALG-2-interacting protein 1; alinx; Alix; apoptosis-linked gene 2-interacting protein X; dopamine receptor interacting protein 4; HP95; KIAA1375; MGC17003; PDCD6-interacting protein; programmed cell death 6 interacting protein; programmed cell death 6-interacting protein

Molecular Weight

Mass (kDA):
96.023 kDA

Genomic Context


Human

Location:	3p22.3
Sequence:	3; NC_000003.12 (33798571..33869707)

Subcellular Localizations

Cytoplasm, cytosol. Melanosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Secreted, extracellular exosome. Cell junction, tight junction. Midbody, Midbody ring. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Colocalized with CEP55 at centrosomes of non-dividing cells. Component of the actomyosin-tight junction complex (By similarity). PDCD6IP targeting to the midbody requires the interaction with CEP55 (PubMed:18641129).