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PDCD1 Antibodies
AND PDCD1 ELISA kits, PDCD1 Proteins
Many biological assays use antibodies to detect PDCD1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDCD1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDCD1 antibodies...
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PDCD1 Infographic by Boster Bio
All PDCD1 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK0959
96 wells/kit, with removable strips.
Cat # EK0959
96 wells/kit, with removable strips.
Human
Flow Cytometry, IF, IHC
$486
Cat # M00178
100ug/vial
Cat # M00178
100ug/vial
Anti-PD-1/PDCD1 Antibody Picoband®
1 Citations
Mouse, Rat
Flow Cytometry, IF, IHC, WB
$370
Cat # A00178
100 μg/vial
Cat # A00178
100 μg/vial
Human, Mouse, Rat
ELISA, IF, IHC-P, WB
$524
Cat # M00178-3
0.1 mg
Cat # M00178-3
0.1 mg
Human
ELISA, IF, IHC-P, ICC, WB
$524
Cat # M00178-4
0.1 mg
Cat # M00178-4
0.1 mg
Cynomolgus monkey, Human
ELISA, Flow Cytometry, FTA
$349
Cat # M00178-6
100 μg
Cat # M00178-6
100 μg
PDCD1 Overview
Facts about Programmed cell death protein 1.
Programmed cell death protein 1 (PDCD1)
Inhibitory cell surface receptor involved in the regulation of T-cell function during tolerance and immunity. Upon ligand binding, inhibits T-cell effector functions in an antigen- specific manner.
Potential cell death inducer, in association with other elements. .
Gene Information
| Human | |
|---|---|
| Gene Name: | PDCD1 |
| Uniprot: | Q15116 |
| Entrez: | 5133 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CD279 antigen; CD279; hPD-1; PD1; PD-1; PD1hPD-l; PDCD1; programmed cell death 1; programmed cell death protein 1; Protein PD-1; SLEB2
Molecular Weight
Mass (kDA):
31.647 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q37.3 |
| Sequence: | 2; NC_000002.12 (241849881..241858908, complement) |
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein.
Diseases
- Neoplasms
- Autoimmune Reaction
- Autoimmune Diseases
- Virus Diseases
- Malignant Neoplasms
- Hiv Infections
- Infective Disorder
- Hepatitis
- Exhaustion
- Lupus Erythematosus, Systemic
- Autoimmunity
- Hepatitis B
- Hepatitis, Chronic
Interacting Proteins
- CD274
- PDCD1LG2
- PTPN11
Pathways
- Cell Death
- Cell Activation
- Immune Response
- Programmed Cell Death
- T Cell Activation
- Cytokine Production
- Cell Proliferation
- Pathogenesis
- Secretion
- T Cell Proliferation
- Cytokine Secretion
- Viral Replication
- Cell Differentiation
PTMs
- Phosphorylation
- Demethylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PDCD1
bosterbio.com/bosterbio-gene-info-cards/PDCD1
References
PMID: 7851902 by Shinohara T., et al. Structure and chromosomal localization of the human PD-1 gene (PDCD1).
PMID: 9332365 by Finger L.R., et al. The human PD-1 gene: complete cDNA, genomic organization, and developmentally regulated expression in B cell progenitors.
1 Publications of Boster PDCD1 Antibodies & ELISA Kits
- PubMed ID: 10.1007/s10753-018-0754-2, Mycophenolate Mofetil Protects Septic Mice via the Dual Inhibition of Inflammato...
*More publications can be found for each product on its corresponding product page