PCSK1 Antibodies

AND PCSK1 ELISA kits, PCSK1 Proteins

Many biological assays use antibodies to detect PCSK1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PCSK1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PCSK1 antibodies...

We validate the specificity of these antibodies to PCSK1 by testing them on tissues known to express PCSK1 positively and negatively. Browse below to find the PCSK1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PCSK1 Infographic by Boster Bio

All PCSK1 Products

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Anti-PC1/3/PCSK1 Antibody Picoband®

7 Q&As

Human, Mouse, Rat

IF, IHC, WB

$370
Cat # PA2084
100 μg/vial

PCSK1 Overview

Facts about Neuroendocrine convertase 1.

PCSK1 3D structure. Source: alphafold

Neuroendocrine convertase 1 (PCSK1)

Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP.

Gene Information

Human
Gene Name:	PCSK1
Uniprot:	P29120
Entrez:	5122

Family

Belongs to:

peptidase S8 family

Alternative Names

NEC1; PCSK1; Proprotein Convertase 1

Molecular Weight

Mass (kDA):
84.152 kDA

Genomic Context


Human

Location:	5q15
Sequence:	5; NC_000005.10 (96390333..96433248, complement)

Subcellular Localizations

Cytoplasmic vesicle, secretory vesicle. Localized in the secretion granules.

Diseases

Obesity
Pituitary Diseases
Neoplasms
Diabetes Mellitus
Vaccinia
Diabetes Mellitus, Non-insulin-dependent
Insulin Resistance
Malignant Neoplasms
Pituitary Neoplasms
Pheochromocytoma
Insulinoma
Sarcoma
Fibrosarcoma

Pediatric Obesity
Insulin Sensitivity
Neoplasm Metastasis
Malnutrition
Malignant Neoplasm Of Breast
Tumor Angiogenesis
Mammary Neoplasms

Pathways

Secretion
Secretory Pathway
Localization
Transport
Regulated Secretory Pathway
Insulin Secretion
Glucose Homeostasis
Constitutive Secretory Pathway
Cell Proliferation
Pathogenesis
Zymogen Activation
Flight
Intracellular Transport

Lactation
Insulin Processing
Angiogenesis
Proteolysis
Eating Behavior
Translation
Cell Differentiation

PTMs

Cleavage
Amidation
Glycosylation
Phosphorylation

Sulphation
Biotinylation
Reduction
Acetylation

Oxidation

Research Areas

Golgi Apparatus Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PCSK1

References

PMID: 1547893 by Creemers J.W.M., et al. Expression in human lung tumor cells of the proprotein processing enzyme PC1/PC3. Cloning and primary sequence of a 5 kb cDNA.

PMID: 1605851 by Seidah N.G., et al. The cDNA sequence of the human pro-hormone and pro-protein convertase PC1.