PCBP1 Antibodies

AND PCBP1 ELISA kits, PCBP1 Proteins

Many biological assays use antibodies to detect PCBP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PCBP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PCBP1 antibodies...

We validate the specificity of these antibodies to PCBP1 by testing them on tissues known to express PCBP1 positively and negatively. Browse below to find the PCBP1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PCBP1 Infographic by Boster Bio

All PCBP1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-PCBP1 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A02636-1
100 μg/vial

Human PCBP1 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ15365
Starting from 20ug

Anti-PCBP1 Mouse Monoclonal Antibody [Clone ID: OTI3D12]

Human, Mouse, Rat

IHC, WB

$523
Cat # M02636
100 µl

Anti-PCBP1 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IP, WB

$370
Cat # M02636-1
100 μl/vial

PCBP1 (NM_006196) Human Over-expression Lysate

Human

$628
Cat # LS005093
100 µg

PCBP1 Overview

Facts about Poly(rC)-binding protein 1.

PCBP1 3D structure. Source: alphafold

Poly(rC)-binding protein 1 (PCBP1)

Single-stranded nucleic acid binding protein which binds preferentially to oligo dC. In case of infection by poliovirus, plays a role in initiation of viral RNA replication in concert with the viral protein 3CD (PubMed:12414943).

Gene Information

Human
Gene Name:	PCBP1
Uniprot:	Q15365
Entrez:	5093

Family

Belongs to:

No superfamily

Alternative Names

alpha-CP1; Heterogeneous nuclear ribonucleoprotein E1; heterogenous nuclear ribonucleoprotein E1; heterogenous nuclear ribonucleoprotein X; hnRNP E1; hnRNP-E1; hnRNP-X; HNRPE1; HNRPX; nucleic acid binding protein sub 2.3; Nucleic acid-binding protein SUB2.3; poly(rC) binding protein 1; poly(rC)-binding protein 1

Molecular Weight

Mass (kDA):
37.498 kDA

Genomic Context


Human

Location:	2p13.3
Sequence:	2; NC_000002.12 (70087477..70089203)

Tissue Specificity

Abundantly expressed in skeletal muscle, thymus and peripheral blood leukocytes while a lower expression is observed in prostate, spleen, testis, ovary, small intestine, heart, liver, adrenal and thyroid glands.

Subcellular Localizations

Nucleus. Cytoplasm. Loosely bound in the nucleus. May shuttle between the nucleus and the cytoplasm.

Diseases

Malignant Neoplasms
Neoplasms
Carcinoma
Neuroblastoma
Folic Acid Deficiency
Liver Neoplasms
Hypoxia
Liver Carcinoma
Malignant Paraganglionic Neoplasm
Tissue Adhesions
Leukemia
Immunologic Deficiency Syndromes
Adenocarcinoma

Tumor Virus Infections
Acute Erythroblastic Leukemia
Cell Invasion
Infective Disorder
Malignant Neoplasm Of Prostate
Nasopharyngeal Neoplasms
Papillomavirus Infections

Interacting Proteins

PAK1
PCBP2
PPIG
PRPF8
PTBP1

PUF60
QKI
RBM39
SNRPA
THAP11

TSC22D4
WBP11
ZNF830

Pathways

Translation
Mrna Stabilization
Localization
Cell Adhesion
Cell Migration
Cell Cycle
Cell Proliferation
Cell Growth
Rna Interference
Transport
Virion Assembly
Gene Silencing
Aging

Immune Response
Regulation Of Gene Expression
Tropism
Nuclear Export
Spermatogenesis
Cell Cycle Arrest
Cell Division

PTMs

Phosphorylation
Cleavage
Reduction

Hydroxylation
Methylation
Ribosylation

Cysteinylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PCBP1

References

PMID: 7607214 by Leffers H., et al. Characterisation of two major cellular poly(rC)-binding human proteins, each containing three K-homologous (KH) domains.

PMID: 7556077 by Kiledjian M., et al. Identification of two KH domain proteins in the alpha-globin mRNP stability complex.