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Paired box protein Pax-8 Antibodies
AND PAX8 ELISA kits, Paired box protein Pax-8 Proteins
Many biological assays use antibodies to detect Paired box protein Pax-8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Paired box protein Pax-8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Paired box protein Pax-8 antibodies...
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PAX8 Infographic by Boster Bio
All PAX8 Products
Product
Figures
Specificity
Applications
Price
Dog, Human
Flow Cytometry, IF, IHC, WB
$486
Cat # M00943
100ug/vial
Cat # M00943
100ug/vial
PAX8 Overview
Facts about Paired box protein Pax-8.
Paired box protein Pax-8 (PAX8)
Transcription factor for the thyroid-specific expression of the genes exclusively expressed in the thyroid cell type, keeping the functional differentiation of such cells. .
Gene Information
| Human | |
|---|---|
| Gene Name: | PAX8 |
| Uniprot: | Q06710 |
| Entrez: | 7849 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
paired box 8; paired box gene 8; paired box protein Pax-8; paired domain gene 8
Molecular Weight
Mass (kDA):
48.218 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q14.1 |
| Sequence: | 2; NC_000002.12 (113215997..113278921, complement) |
Tissue Specificity
Expressed in the excretory system, thyroid gland and Wilms tumors.
Subcellular Localizations
Nucleus.
Diseases
- Neoplasms
- Carcinoma
- Thyroid Neoplasm
- Malignant Neoplasms
- Malignant Neoplasm Of Thyroid
- Hypothyroidism
- Congenital Hypothyroidism
- Follicular Thyroid Carcinoma
- Carcinoma, Papillary
- Adenoma
- Congenital Abnormality
- Malignant Paraganglionic Neoplasm
Interacting Proteins
- NCL
- SERINC1
Pathways
- Pathogenesis
- Cell Proliferation
- Kidney Development
- Cell Differentiation
- Cell Growth
- Localization
- Gland Development
- Ear Development
- Translation
- Gastrulation
- Dedifferentiation
- Cell Cycle
- Thyroid Gland Development
PTMs
- Phosphorylation
- Methylation
- Reduction
- Glutathionylation
- Acetylation
Research Areas
- Cancer
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PAX8
bosterbio.com/bosterbio-gene-info-cards/PAX8
References
PMID: 1337742 by Poleev A., et al. PAX8, a human paired box gene: isolation and expression in developing thyroid, kidney and Wilms' tumors.
PMID: 8413205 by Kozmik Z., et al. Alternative splicing of Pax-8 gene transcripts is developmentally regulated and generates isoforms with different transactivation properties.