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Paired box protein Pax-5 Antibodies
AND PAX5 ELISA kits, Paired box protein Pax-5 Proteins
Many biological assays use antibodies to detect Paired box protein Pax-5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Paired box protein Pax-5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Paired box protein Pax-5 antibodies...
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PAX5 Infographic by Boster Bio
All PAX5 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00669
100 μl
Cat # M00669
100 μl
Human, Mouse, Rat
ELISA, IF, IHC, ICC, WB
$370
Cat # A00669-1
100 μg/vial
Cat # A00669-1
100 μg/vial
Human
IHC, WB
$431
Cat # M00669-1
100uL
Cat # M00669-1
100uL
Human, Mouse
ELISA
$480
Cat # EKC1442
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1442
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M00669-2
100 μg/vial
Cat # M00669-2
100 μg/vial
Human, Mouse
Flow Cytometry, IF, IHC, ICC, WB
$405
Cat # A00669
100ul
Cat # A00669
100ul
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A00669-2
100 µg/vial
Cat # A00669-2
100 µg/vial
PAX5 Overview
Facts about Paired box protein Pax-5.
Paired box protein Pax-5 (PAX5)
May play an important role in B-cell differentiation in addition to neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | PAX5 |
| Uniprot: | Q02548 |
| Entrez: | 5079 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
B cell specific activator protein; B-cell-specific transcription factor; BSAP; BSAPB-cell lineage specific activator; paired box 5; paired box gene 5 (B-cell lineage specific activator protein); paired box gene 5 (B-cell lineage specific activator); paired box homeotic gene 5; paired box protein Pax-5; Pax5; transcription factor PAX 5
Molecular Weight
Mass (kDA):
42.149 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9p13.2 |
| Sequence: | 9; NC_000009.12 (36833269..37034268, complement) |
Subcellular Localizations
Nucleus.
Diseases
- Lymphoma
- Neoplasms
- Leukemia
- B-cell Lymphomas
- Malignant Neoplasms
- Acute Lymphocytic Leukemia
- Diffuse Large B-cell Lymphoma
- Malignant Paraganglionic Neoplasm
- Hodgkin Disease
- Chromosomal Translocation
- Cell Transformation, Neoplastic
- Lymphoma, Non-hodgkin
- Precursor B-cell Lymphoblastic Leukemia-lymphoma
Interacting Proteins
- KMT2A
Pathways
- Cell Development
- Cell Differentiation
- B Cell Differentiation
- Pathogenesis
- Methylation
- Plasma Cell Differentiation
- Cell Proliferation
- Cell Cycle
- Immune Response
- Secretion
- Dna Methylation
- Oncogenesis
- B Cell Lineage Commitment
PTMs
- Methylation
- Phosphorylation
- Acetylation
- Demethylation
- Phosphorothioation
- Cleavage
Research Areas
- Cancer
- Transcription Factors and Regulators
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PAX5
bosterbio.com/bosterbio-gene-info-cards/PAX5
References
PMID: 1516825 by Adams B., et al. Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis.
PMID: 15385562 by Robichaud G.A., et al. Human Pax-5 C-terminal isoforms possess distinct transactivation properties and are differentially modulated in normal and malignant B cells.