Paired box protein Pax-3 Antibodies

AND PAX3 ELISA kits, Paired box protein Pax-3 Proteins

Many biological assays use antibodies to detect Paired box protein Pax-3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Paired box protein Pax-3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Paired box protein Pax-3 antibodies...

We validate the specificity of these antibodies to Paired box protein Pax-3 by testing them on tissues known to express PAX3 positively and negatively. Browse below to find the PAX3 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PAX3 Infographic by Boster Bio

All PAX3 Products

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Product

Figures

Specificity

Applications

Price

Anti-PAX3 Antibody Picoband®

1 Citations

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A00285-1
100 μg/vial

Anti-PAX3 Antibody (N-term)

Human

Flow Cytometry, IHC-P, WB

$299
Cat # A00285
80 µl

PAX3 (NM_181457) Human Over-expression Lysate

Human

$960
Cat # LS005077
100 µg

Anti-PAX3 Antibody Picoband®

Human

ELISA, IF, ICC, WB

$370
Cat # A00285-2
100 µg/vial

PAX3 Overview

Facts about Paired box protein Pax-3.

PAX3 3D structure. Source: alphafold

Paired box protein Pax-3 (PAX3)

Transcription factor that may regulate cell proliferation, migration and apoptosis. Involved in neural development and myogenesis.

Transcriptional activator of MITF, acting synergistically with SOX10 (PubMed:21965087). .

Gene Information

Human
Gene Name:	PAX3
Uniprot:	P23760
Entrez:	5077

Family

Belongs to:

paired homeobox family

Alternative Names

CDHS; HUP2; HUP2MGC120384; MGC120381; MGC120382; MGC120383; MGC134778; paired box 3; paired box gene 3 (Waardenburg syndrome 1); paired box homeotic gene 3; paired box protein Pax-3; paired domain gene 3; paired domain gene HuP2; Pax3; Waardenburg syndrome 1; WS1; WS3

Molecular Weight

Mass (kDA):
52.968 kDA

Genomic Context


Human

Location:	2q36.1
Sequence:	2; NC_000002.12 (222199887..222298998, complement)

Subcellular Localizations

Nucleus.

Diseases

Rhabdomyosarcoma
Neoplasms
Crest Syndrome
Alveolar Rhabdomyosarcoma
Waardenburg Syndrome
Chromosomal Translocation
Malignant Neoplasms
Rhabdomyosarcoma, Embryonal
Waardenburg Syndrome, Type I (disorder)
Melanoma
Cell Transformation, Neoplastic
Sarcoma

Nervousness
Malignant Paraganglionic Neoplasm
Congenital Abnormality
Complete Hearing Loss
Neoplasm Metastasis
Sensorineural Hearing Loss (disorder)
Tissue Adhesions

Interacting Proteins

POU3F2
SOX10

Pathways

Regeneration
Cell Proliferation
Neural Tube Closure
Tube Closure
Cell Differentiation
Neurogenesis
Pigmentation
Cell Migration
Cell Death
Pathogenesis
Cell Cycle
Localization
Delamination

Gastrulation
Cell Adhesion
Methylation
Segmentation
Cell Growth
Oncogenesis
Somitogenesis

PTMs

Phosphorylation
Methylation
Acetylation
Cleavage
Ubiquitination

Deacetylation
Glycosylation
Sumoylation
Demethylation
Ribosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PAX3

References

PMID: 14639621 by Parker C.J., et al. Expression of PAX 3 alternatively spliced transcripts and identification of two new isoforms in human tumors of neural crest origin.

PMID: 7782066 by Macina R.A., et al. Genomic organization of the human PAX3 gene: DNA sequence analysis of the region disrupted in alveolar rhabdomyosarcoma.

1 Publications of Boster Paired box protein Pax-3 Antibodies & ELISA Kits

PubMed ID: 24126784, Zhang Rp, Liu Hh, Wang Hh, Wang Y, Han Cc, Li L, He H, Xu Hy, Xu F, Wang Jw. Mol...

*More publications can be found for each product on its corresponding product page