Homeobox protein OTX1 Antibodies

AND OTX1 ELISA kits, Homeobox protein OTX1 Proteins

Many biological assays use antibodies to detect Homeobox protein OTX1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Homeobox protein OTX1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Homeobox protein OTX1 antibodies...

We validate the specificity of these antibodies to Homeobox protein OTX1 by testing them on tissues known to express OTX1 positively and negatively. Browse below to find the OTX1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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OTX1 Infographic by Boster Bio

All OTX1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Otx1 Rabbit Monoclonal Antibody

Human, Mouse, Rat

$370
Cat # M05601
100 μl

Anti-Otx1/2 Monoclonal Antibody

5 Q&As

Human, Mouse, Rat

IHC, WB

$370
Cat # M05601-1
100 μl

OTX1 (NM_014562) Human Over-expression Lysate

Human

$628
Cat # LS005013
100 µg

OTX1 Overview

Facts about Homeobox protein OTX1.

OTX1 3D structure. Source: alphafold

Homeobox protein OTX1 (OTX1)

Probably plays a role in the evolution of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.

Gene Information

Human
Gene Name:	OTX1
Uniprot:	P32242
Entrez:	5013

Family

Belongs to:

paired homeobox family

Alternative Names

FLJ38361; homeobox protein OTX1; MGC15736; orthodenticle (Drosophila) homolog 1; orthodenticle homeobox 1; orthodenticle homolog 1 (Drosophila); Orthodenticle homolog 1

Molecular Weight

Mass (kDA):
37.327 kDA

Genomic Context


Human

Location:	2p15
Sequence:	2; NC_000002.12 (63049735..63057831)

Tissue Specificity

Expressed in brain. Detected in the anterior part of the neural fetal retina (at protein level).

Subcellular Localizations

Nucleus.

Diseases

Nervousness
Epilepsy
Neoplasms
Pituitary Diseases
Malignant Neoplasms
Eye Abnormalities
Congenital Neurologic Anomalies
Epiphysis Disorders
Microphthalmos
Carcinoma
Impairment (finding)

Macule
Dysplasia
Medulloblastoma
Malignant Paraganglionic Neoplasm
Otocephaly
Acute Erythroblastic Leukemia

Pathways

Brain Development
Gastrulation
Regionalization
Brain Morphogenesis
Neurogenesis
Head Development
Cell Differentiation
Organ Development
Ear Development
Segmentation
Cell Proliferation
Localization
Cell Death

Ear Morphogenesis
Eye Development
Regeneration
Organ Formation
Inner Ear Morphogenesis
Inner Ear Development
Translation

PTMs

Phosphorylation
Cleavage

Acetylation
Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/OTX1

References

PMID: 8101484 by Simeone A., et al. A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo.

PMID: 19414065 by Larsen K.B., et al. Expression of the homeobox genes PAX6, OTX2, and OTX1 in the early human fetal retina.