Deubiquitinase OTUD6B Antibodies

AND OTUD6B ELISA kits, Deubiquitinase OTUD6B Proteins

Many biological assays use antibodies to detect Deubiquitinase OTUD6B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Deubiquitinase OTUD6B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Deubiquitinase OTUD6B antibodies...

We validate the specificity of these antibodies to Deubiquitinase OTUD6B by testing them on tissues known to express OTUD6B positively and negatively. Browse below to find the OTUD6B antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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OTUD6B Infographic by Boster Bio

All OTUD6B Products

Product

Figures

Specificity

Applications

Price

OTUD6B (NM_016023) Human Recombinant Protein

$1249
Cat # PROTQ8N6M0
20 µg

OTUD6B (NM_016023) Human Over-expression Lysate

Human

$628
Cat # LS051633
100 µg

OTUD6B Overview

Facts about Deubiquitinase OTUD6B.

OTUD6B 3D structure. Source: alphafold

Deubiquitinase OTUD6B (OTUD6B)

Isoform 1: Deubiquitinating enzyme that may play a role in the ubiquitin-dependent regulation of protein synthesis, downstream of mTORC1 (PubMed:21267069, PubMed:27864334). May associate with the protein synthesis initiation complex and change its ubiquitination to repress translation (PubMed:27864334).

May also repress DNA synthesis and alter different cellular targets thereby regulating cell growth and proliferation (PubMed:27864334). May also play a role in proteasome assembly and function (PubMed:28343629).

Gene Information

Human
Gene Name:	OTUD6B
Uniprot:	Q8N6M0
Entrez:	51633

Family

Belongs to:

No superfamily

Alternative Names

CGI-77; DUBA5DUBA-5; OTU domain containing 6B; OTU domain-containing protein 6B

Molecular Weight

Mass (kDA):
33.813 kDA

Genomic Context


Human

Location:	8q21.3
Sequence:	8; NC_000008.11 (91070305..91087095)

Diseases

Intellectual developmental disorder with dysmorphic facies, seizures, and distal limb anomalies (IDDFSDA)

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/OTUD6B

References

PMID: 23827681 by Mevissen T.E., et al. OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis.

PMID: 21267069 by Xu Z., et al. Evidence for OTUD-6B participation in B lymphocytes cell cycle after cytokine stimulation.