ONECUT2 Antibodies

AND ONECUT2 ELISA kits, ONECUT2 Proteins

Many biological assays use antibodies to detect ONECUT2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ONECUT2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ONECUT2 antibodies...

We validate the specificity of these antibodies to ONECUT2 by testing them on tissues known to express ONECUT2 positively and negatively. Browse below to find the ONECUT2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ONECUT2 Infographic by Boster Bio

All ONECUT2 Products

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Product

Figures

Specificity

Applications

Price

Anti-ONECUT2 Antibody Picoband®

6 Q&As

Human, Mouse

$370
Cat # A09652-1
100 μg/vial

ONECUT2 (NM_004852) Human Over-expression Lysate

Human

$960
Cat # LS009480
100 µg

ONECUT2 Overview

Facts about One cut domain family member 2.

ONECUT2 3D structure. Source: alphafold

One cut domain family member 2 (ONECUT2)

Transcriptional activator. Activates the transcription of a number of liver enzymes like HNF3B.

Gene Information

Human
Gene Name:	ONECUT2
Uniprot:	O95948
Entrez:	9480

Family

Belongs to:

CUT homeobox family

Alternative Names

one cut domain family member 2; HNF-6B; OC2; OC-2; one cut homeobox 2; ONECUT2

Molecular Weight

Mass (kDA):
54.303 kDA

Genomic Context


Human

Location:	18q21.31
Sequence:	18; NC_000018.10 (57435374..57491298)

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Neoplasms
Nervousness
Diabetes Mellitus
Prediabetes Syndrome
Waardenburg Syndrome
Melanoma
Malignant Neoplasm Of Breast
Germinal Center B-cell-like Diffuse Large B-cell Lymphoma
Malignant Neoplasm Of Lung
Carcinogenesis
5,10-methylenetetrahydrofolate Reductase Deficiency
Mammary Neoplasms

Lymphoma
Anaplasia
Malignant Neoplasm Of Prostate
Glioblastoma Multiforme
Hereditary Diseases
Lung Neoplasms
Failure To Thrive

Pathways

Liver Development
Pancreas Development
Hepatocyte Differentiation
Dna Methylation
Methylation
Transport
Pancreas Morphogenesis
Cell Dedifferentiation
Gene Silencing
Melanocyte Differentiation
Insulin Secretion
Cell Fate Determination
Neurogenesis

Regulation Of Gene Expression
Neuron Development
Cell Cycle
Dedifferentiation
Hepatoblast Differentiation
Pathogenesis
Exocytosis

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ONECUT2

References

PMID: 9915796 by Jacquemin P., et al. OC-2, a novel mammalian member of the ONECUT class of homeodomain transcription factors whose function in liver partially overlaps with that of hepatocyte nuclear factor-6.