ONECUT1 Antibodies

AND ONECUT1 ELISA kits, ONECUT1 Proteins

Many biological assays use antibodies to detect ONECUT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ONECUT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ONECUT1 antibodies...

We validate the specificity of these antibodies to ONECUT1 by testing them on tissues known to express ONECUT1 positively and negatively. Browse below to find the ONECUT1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ONECUT1 Infographic by Boster Bio

All ONECUT1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-HNF6/ONECUT1 Antibody Picoband®

1 Q&As

Human, Mouse, Rat

$370
Cat # PA2214
100 μg/vial

Anti-HNF6 (ONECUT1) Mouse Monoclonal Antibody [Clone ID: OTI4F12]

Human, Mouse, Rat

IF, IHC, WB

$523
Cat # M07349
100 µl

HNF6 (ONECUT1) (NM_004498) Human Over-expression Lysate

Human

$960
Cat # LS003175
100 µg

Anti-ONECUT1 Antibody Picoband®

Human

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A07349
100 µg/vial

ONECUT1 Overview

Facts about Hepatocyte nuclear factor 6.

ONECUT1 3D structure. Source: alphafold

Hepatocyte nuclear factor 6 (ONECUT1)

Transcriptional activator. Binds the consensus sequence 5'-DHWATTGAYTWWD-3' on an assortment of gene promoters such as those of HNF3B and TTR.

Important for liver genes transcription. .

Gene Information

Human
Gene Name:	ONECUT1
Uniprot:	Q9UBC0
Entrez:	3175

Family

Belongs to:

CUT homeobox family

Alternative Names

HNF6; HNF-6; HNF-6A; HNF6Ahepatocyte nuclear factor 6, alpha; HNF6hepatocyte nuclear factor 6; HNF-6One cut domain family member 1; OC-1; one cut homeobox 1one cut domain, family member 1; ONECUT1

Molecular Weight

Mass (kDA):
51.023 kDA

Genomic Context


Human

Location:	15q21.3
Sequence:	15; NC_000015.10 (52755053..52790336, complement)

Tissue Specificity

Highly expressed in liver; lower expression in testis and skin.

Subcellular Localizations

Nucleus.

Diseases

Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Liver Carcinoma
Liver Neoplasms
Cholestasis
Neoplasms
Congenital Abnormality
Tissue Adhesions
Diverticulum
Maturity Onset Diabetes Mellitus In Young
Malignant Neoplasms
Pituitary Diseases
Adenovirus Infections

Liver Diseases
Fibrosis
Injury To Liver
Anaplasia
Nervousness
Liver Regeneration Disorder
Adenocarcinoma

Pathways

Liver Development
Pancreas Development
Cell Differentiation
Secretion
Glucose Homeostasis
Hepatocyte Differentiation
Insulin Secretion
Gluconeogenesis
Intrahepatic Bile Duct Development
Dedifferentiation
Transport
Methylation
Regeneration

Coagulation
Hepatoblast Differentiation
Pathogenesis
Cell Adhesion
Pancreas Morphogenesis
Cell Migration
Neurogenesis

PTMs

Methylation

Phosphorylation

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ONECUT1

References

PMID: 10491763 by Moeller A.M., et al. Hepatocyte nuclear factor-6: associations between genetic variability and type II diabetes and between genetic variability and estimates of insulin secretion.