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- Table of Contents
Facts about Obg-like ATPase 1.
.
Human | |
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Gene Name: | OLA1 |
Uniprot: | Q9NTK5 |
Entrez: | 29789 |
Belongs to: |
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TRAFAC class OBG-HflX-like GTPase superfamily |
DKFZp313H1942; DNA damage-regulated overexpressed in cancer 45 protein; DOC45; EC 3.6.3; EC 3.6.3.-; GBP45; GTP-binding protein 9 (putative); GTP-binding protein 9; GTP-binding protein PTD004; GTPBP9; homologous yeast-44.2 protein; Obg-like ATPase 1; PTD004
Mass (kDA):
44.744 kDA
Human | |
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Location: | 2q31.1 |
Sequence: | 2; NC_000002.12 (174072447..174248532, complement) |
Expressed in all tissues tested but its expression is more abundant in testis, liver, lung, and brain. Overexpressed in several malignancies, including cancers of the colon, rectum, ovary, lung, stomach, and uterus.
Cytoplasm. Nucleus. Nucleus, nucleolus. Predominantly cytoplasmic, shuttles between the nucleus and the cytoplasm.
PMID: 20053727 by Sun H., et al. DOC45, a novel DNA damage-regulated nucleocytoplasmic ATPase that is overexpressed in multiple human malignancies.
PMID: 17430889 by Koller-Eichhorn R., et al. Human OLA1 defines an ATPase subfamily in the Obg family of GTP- binding proteins.