NSMF Antibodies

AND NSMF ELISA kits, NSMF Proteins

Many biological assays use antibodies to detect NSMF, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NSMF in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NSMF antibodies...

We validate the specificity of these antibodies to NSMF by testing them on tissues known to express NSMF positively and negatively. Browse below to find the NSMF antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NSMF Infographic by Boster Bio

All NSMF Products

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Product

Figures

Specificity

Applications

Price

NELF (NSMF) (NM_015537) Human Over-expression Lysate

Human

$628
Cat # LS026012
100 µg

Anti-NELF/NSMF Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A08385-1
100 µg/vial

NSMF Overview

Facts about NMDA receptor synaptonuclear signaling and neuronal migration factor.

NSMF 3D structure. Source: alphafold

NMDA receptor synaptonuclear signaling and neuronal migration factor (NSMF)

Couples NMDA-sensitive glutamate receptor signaling to the nucleus and causes long-lasting changes in the cytoarchitecture of dendrites and spine synapse processes. Part of the cAMP response element-binding protein (CREB) shut-off signaling pathway.

Stimulates outgrowth of olfactory axons and migration of gonadotropin-releasing hormone (GnRH) and luteinizing-hormone-releasing hormone (LHRH) neuronal cells. .

Gene Information

Human
Gene Name:	NSMF
Uniprot:	Q6X4W1
Entrez:	26012

Family

Belongs to:

NSMF family

Alternative Names

NMDA receptor synaptonuclear signaling and neuronal migration factor

Molecular Weight

Mass (kDA):
60.143 kDA

Genomic Context


Human

Location:	9q34.3
Sequence:	9; NC_000009.12 (137447570..137459334, complement)

Tissue Specificity

Highly expressed in adult and fetal brain. Weakly expressed in heart, liver, spleen, testis, small intestine, skeletal muscle, peripheral white blood cells and kidney.

Subcellular Localizations

Nucleus. Nucleus envelope. Nucleus membrane. Nucleus matrix. Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein. Cell projection, dendrite. Cell junction, synapse. Cell junction, synapse, synaptosome. Cell junction, synapse, postsynaptic density. Membrane. Found on the outside of the luteinizing-hormone-releasing hormone (LHRH) cell membrane and axons projecting from the olfactory pit and epithelium. Associates with transcriptionally active chromatin regions. Detected at the nuclear membranes of CA1 neurons. Cortical cytoskeleton. Localized i

Diseases

Hypogonadotropic hypogonadism 9 with or without anosmia (HH9)

PTMs

Lipoprotein

Myristate

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NSMF

References

PMID: 15362570 by Miura K., et al. Characterization of the human nasal embryonic LHRH factor gene, NELF, and a mutation screening among 65 patients with idiopathic hypogonadotropic hypogonadism (IHH).

PMID: 20025934 by Xu N., et al. NELF is a nuclear protein involved in hypothalamic GnRH neuronal migration.