Nucleoplasmin-3 Antibodies

AND NPM3 ELISA kits, Nucleoplasmin-3 Proteins

Many biological assays use antibodies to detect Nucleoplasmin-3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nucleoplasmin-3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nucleoplasmin-3 antibodies...

We validate the specificity of these antibodies to Nucleoplasmin-3 by testing them on tissues known to express NPM3 positively and negatively. Browse below to find the NPM3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NPM3 Infographic by Boster Bio

All NPM3 Products

Product

Figures

Specificity

Applications

Price

NPM3 (NM_006993) Human Recombinant Protein

$1249
Cat # PROTO75607
20 µg

NPM3 (NM_006993) Human Over-expression Lysate

Human

$628
Cat # LS010360
100 µg

NPM3 Overview

Facts about Nucleoplasmin-3.

NPM3 3D structure. Source: alphafold

Nucleoplasmin-3 (NPM3)

May act as a chaperone. .

Gene Information

Human
Gene Name:	NPM3
Uniprot:	O75607
Entrez:	10360

Family

Belongs to:

nucleoplasmin family

Alternative Names

nucleophosmin/nucleoplasmin 3; nucleophosmin/nucleoplasmin family, member 3; nucleoplasmin-3; PORMIN; TMEM123

Molecular Weight

Mass (kDA):
19.344 kDA

Genomic Context


Human

Location:	10q24.32
Sequence:	10; NC_000010.11 (101781325..101783413, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Nucleus. Nucleus, nucleolus. Mainly found in the granular component of the nucleolus.

Diseases

Neoplasms
Malignant Neoplasms
Sarcoma
Carcinoma
Mammary Neoplasms
Cell Transformation, Neoplastic
Malignant Paraganglionic Neoplasm
Stomach Neoplasms
Mutation Abnormality
Neoplasm Metastasis
Myxoid Dermatofibrosarcoma Protuberans

Carcinogenesis
Fibrosarcoma
Animal Mammary Neoplasms
Chondrosarcoma
Hemosiderosis
Retroviridae Infections

Interacting Proteins

NPM2

Pathways

Chromatin Remodeling
Localization
Fertilization
Ribosome Biogenesis
Nucleosome Assembly
Cell Proliferation
Gene Silencing
Chromatin Disassembly
Sperm Chromatin Decondensation
Reverse Transcription
Translation

Cell Differentiation
Mrna Processing
Centrosome Duplication
Pathogenesis
Chromatin Assembly
Rrna Transcription

PTMs

Phosphorylation

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NPM3

References

PMID: 11722795 by Shackleford G.M., et al. Cloning, expression and nuclear localization of human NPM3, a member of the nucleophosmin/nucleoplasmin family of nuclear chaperones.

PMID: 15596447 by Huang N., et al. Protein NPM3 interacts with the multifunctional nucleolar protein B23/nucleophosmin and inhibits ribosome biogenesis.