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NADPH oxidase 4 Antibodies
AND Nox4 ELISA kits, NADPH oxidase 4 Proteins
Many biological assays use antibodies to detect NADPH oxidase 4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NADPH oxidase 4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NADPH oxidase 4 antibodies...
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Nox4 Infographic by Boster Bio
All Nox4 Products
Product
Figures
Specificity
Applications
Price
Anti-NADPH oxidase 4/NOX4 Antibody Picoband®
2 Citations 5 Q&As
Human, Mouse, Rat
Flow Cytometry, IHC, IHC-F, ICC, WB
$370
Cat # PA1929
100 μg/vial
Cat # PA1929
100 μg/vial
Anti-NOX4 Rabbit Monoclonal Antibody
4 Citations 18 Q&As
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$370
Cat # M00403
100 μl
Cat # M00403
100 μl
Anti-NADPH oxidase 4/NOX4 Antibody Picoband®
6 Citations 16 Q&As
Human, Monkey
IF, ICC, WB
$370
Cat # A00403
100 μg/vial
Cat # A00403
100 μg/vial
Nox4 Overview
Facts about NADPH oxidase 4.
NADPH oxidase 4 (Nox4)
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades likely through phosphatases inhibition.
May be the oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Nox4 |
| Uniprot: | Q9JHI8 |
| Entrez: | 50490 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
EC 1.6.3; Kidney oxidase-1; Kidney superoxide-producing NADPH oxidase; KOX; KOX-1; KOX-1Renal NAD(P)H-oxidase; NADPH oxidase 4; Nox4; RENOX; RENOXEC 1.6.3.-
Molecular Weight
Mass (kDA):
66.519 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 7|7 D3 |
| Sequence: | 7; |
Tissue Specificity
EXpressed in brain, in all layers of the cerebellum, in pyramidal cells of the Ammon horn and in Purkinje cells (at protein level). Expressed in osteoclasts, leukocytes, kidney, liver and lung.
Diseases
- Hypertensive Disease
- Inflammation
- Fibrosis
- Diabetes Mellitus
- Hypertrophy
- Cardiovascular Diseases
- Atherosclerosis
- Malignant Neoplasms
- Kidney Diseases
- Neoplasms
- Hypoxia
- Vascular Diseases
Pathways
- Pathogenesis
- Cell Proliferation
- Cell Death
- Angiogenesis
- Localization
- Transport
- Secretion
- Excretion
- Senescence
- Cell Cycle
- Electron Transport
- Cell Migration
- Aging
PTMs
- Phosphorylation
- Oxidation
- Cleavage
- Reduction
- Dephosphorylation
- Nitrosylation
- Phosphorothioation
Research Areas
- Cancer
- Cell Biology
- Diabetes Research
- Hypoxia
- Lipid and Metabolism
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Nox4
bosterbio.com/bosterbio-gene-info-cards/Nox4
References
PMID: 10869423 by Geiszt M., et al. Identification of renox, an NAD(P)H oxidase in kidney.
PMID: 11032835 by Shiose A., et al. A novel superoxide-producing NAD(P)H oxidase in kidney.
7 Publications of Boster NADPH oxidase 4 Antibodies & ELISA Kits
- PubMed ID: 10.1097/FJC.0000000000000534, Suppression of Oxidative Stress and Apoptosis in Electrically Stimulated Neonata...
- PubMed ID: 10.1016/j.ijbiomac.2016.05.002, Bletilla striata polysaccharide inhibits angiotensin II-induced ROS and inflamma...
- PubMed ID: 10.1016/j.abb.2017.06.017, Polydatin protects against carbon tetrachloride-induced liver fibrosis in mice
- PubMed ID: 31398421, Wang D,Yan Z,Bu L,An C,Deng B,Zhang J,Rao J,Cheng L,Zhang J,Zhang B,Xie J.Protec...
- PubMed ID: 29963902, Deficiency of NOX1 or NOX4 Prevents Liver Inflammation and Fibrosis in Mice thro...
- PubMed ID: 27803283, Obligatory role for GPER in cardiovascular aging and disease^
- PubMed ID: 28666738, Zhao, X., Li, R., Liu, Y., Zhang, X., Zhang, M., Zeng, Z.,…, & Wang, Y. (2017)...
*More publications can be found for each product on its corresponding product page