NUAK1 Antibodies

AND NUAK1 ELISA kits, NUAK1 Proteins

Many biological assays use antibodies to detect NUAK1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NUAK1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NUAK1 antibodies...

We validate the specificity of these antibodies to NUAK1 by testing them on tissues known to express NUAK1 positively and negatively. Browse below to find the NUAK1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NUAK1 Infographic by Boster Bio

All NUAK1 Products

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Product

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Specificity

Applications

Price

Anti-NUAK family SNF1-like kinase 1 NUAK1 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A03575
100ul

ARK5 (NUAK1) (NM_014840) Human Over-expression Lysate

Human

$960
Cat # LS009891
100 µg

NUAK1 Overview

Facts about NUAK family SNF1-like kinase 1.

NUAK1 3D structure. Source: alphafold

NUAK family SNF1-like kinase 1 (NUAK1)

Serine/threonine-protein kinase involved in various processes like cell adhesion, regulation of cell ploidy and senescence, cell proliferation and tumor progression. Acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of'Ser-464' of LATS1, thereby controlling its stability.

Controls cell adhesion by regulating activity of the myosin protein phosphatase 1 (PP1) complex. Acts by mediating phosphorylation of PPP1R12A subunit of myosin PP1: phosphorylated PPP1R12A then interacts with 14-3-3, leading to decreased dephosphorylation of myosin MLC2 by myosin PP1.

Gene Information

Human
Gene Name:	NUAK1
Uniprot:	O60285
Entrez:	9891

Family

Belongs to:

protein kinase superfamily

Alternative Names

AMPK-related protein kinase 5; ARK5; ARK5AMP-activated protein kinase family member 5; EC 2.7.11; EC 2.7.11.1; KIAA0537NUAK family SNF1-like kinase 1; NUAK family, SNF1-like kinase, 1; NUAK1

Molecular Weight

Mass (kDA):
74.305 kDA

Genomic Context


Human

Location:	12q23.3
Sequence:	12; NC_000012.12 (106063347..106140033, complement)

Tissue Specificity

Expressed at high levels in heart and brain, and at lower levels in skeletal muscle, kidney, ovary, placenta, lung and liver. Highly up-regulated in colorectal cancer cell lines.