Neurotrophin-4 Antibodies

Neurotrophin-4 (NTF4)

Target-derived survival factor for peripheral sensory sympathetic neurons. .

Gene Information

Human
Gene Name:	NTF4
Uniprot:	P34130
Entrez:	4909

Family

Belongs to:
NGF-beta family

Alternative Names

GLC10; GLC1O; neurotrophic factor 4; neurotrophic factor 5; neurotrophin 4; neurotrophin 5 (neurotrophin 4/5); neurotrophin-4; neurotrophin-5; Neutrophic factor 4; NT4; NT-4; NT-4/5; NT-5; NTF4; NTF5; NTF5NT5

Molecular Weight

Mass (kDA):
22.427 kDA

Genomic Context

Human
Location:	19q13.33
Sequence:	19; NC_000019.10 (49058284..49065076, complement)

Tissue Specificity

Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.

Subcellular Localizations

Secreted.

Diseases

• Glaucoma
• Glaucoma, Open-angle
• Primary Open Angle Glaucoma
• Intraocular Pressure Disorder
• Nervousness
• Disorder Of The Optic Nerve
• Attention Deficit Hyperactivity Disorder
• Blind Vision
• Eating Disorders
• Dehydration
• Neuronal Migration Disorders

• Spherophakia
• Maternal Exposure
• Inattention
• Glaucoma Of Childhood
• Asthma

Interacting Proteins

• BDNF
• NTRK2

Pathways

• Germination
• Pathogenesis
• Pollen Germination
• Defense Response
• Cell Death
• Pollen Maturation
• Cell Division
• System Development
• Cell Cycle
• Cell Adhesion
• Response To Wounding
• Pollen Hydration
• Programmed Cell Death

• Pollen Development
• Lactation
• Brain Development
• Neurogenesis
• Eating Behavior
• Respiratory Burst
• Localization

PTMs

• Phosphorylation

• Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NTF4

Boster Bio: Best Uses Of The NTF4 Marker

Are you interested in learning more about the Boster Bio: Best Uses Of TheNTF4 Marker? You have come to the right spot if you are. This article will give you some useful information about the NTF4 marker and the use of anti-it antibodies. Learn more about this biological marker that is highly effective and how you can make the most of it.

NTF4 antibody

Boster Bio NTF4 antibody (monoclonal antibody) is directed against the human neurotrophin-4, or NTF4, protein. This antibody recognizes N-terminal variable domains (N-terminal) of human NT-4, a protein important for the survival of and differentiation of neurons. This protein may also be important for long term memory and therapeutics for acquired disorders of the brain. This antibody is extremely specific, but does not cross-react or interact with other proteins.

NTRK2 antibody

Anti-NTRK2 antibody makes a powerful tool for diagnosis, research, as well as other applications. It reacts with Human, Mouse, Rat, and is suitable for use in WB and IHC-P applications. It is supplied in PBS with 0.09% sodium azide and is purified using a protein G column. NTRK2 antibody was derived from mice that have been immunized with recombinant proteins. It can also be used to block antibodies from binding to other proteins.

Boster bioengineering of PR China has developed a monoclonal antibodies that recognizes BDNF (Twist), and NTRK2. This rabbit polyclonal monoclonal antibody was validated in Immunocytochemistry (Immunofluorescence) and is suitable to a wide range o clinical samples. Its Supervision Polymer-based Secondary Antibody reduces IHC processing by 30 minutes. The Picoband technology is powered by the company's extensive insights into immunogen design and backed by technical support from BeNeLux distributor Sanbio.

The NTRK2 protein is essential for the development and maintenance of the central nervous system, where it regulates neuron survival, growth, differentiation, migration, and synapse formation. Studies have shown a positive association between NTRK2 protein transcription and depression. This is a condition where cognitive function is impaired. The Boster Bio NTRK2 antibody is recommended for researchers seeking to target NTRK2 in clinical studies.

The antibody recognizes one subset of neurotrophins. It is effective against a variety disease. The main cause of obesity is also neurotrophins. These neurotrophins regulate cell differentiation. Mutations in the gene can also be linked to depression and irritable bowel syndrome. It is essential for drug development and research. It is used in many fields. Download our free trial version today to test the BosterBio NTRK2 antibodies.