NT5C Antibodies

AND NT5C ELISA kits, NT5C Proteins

Many biological assays use antibodies to detect NT5C, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NT5C in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NT5C antibodies...

We validate the specificity of these antibodies to NT5C by testing them on tissues known to express NT5C positively and negatively. Browse below to find the NT5C antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NT5C Infographic by Boster Bio

All NT5C Products

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Product

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Specificity

Applications

Price

NT5C (NM_014595) Human Over-expression Lysate

Human

$628
Cat # LS030833
100 µg

Anti-NT5C Antibody Picoband®

Human

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A10650-1
100 µg/vial

NT5C Overview

Facts about 5'(3')-deoxyribonucleotidase, cytosolic type.

NT5C 3D structure. Source: alphafold

5'(3')-deoxyribonucleotidase, cytosolic type (NT5C)

Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP. .

Gene Information

Human
Gene Name:	NT5C
Uniprot:	Q8TCD5
Entrez:	30833

Family

Belongs to:

5'(3')-deoxyribonucleotidase family

Alternative Names

3'-pyrimidine nucleotidase; 5' nucleotidase, deoxy (pyrimidine), cytosolic type C; 5', 3'-nucleotidase, cytosolic; cdN; Cytosolic 5'; Deoxy-5'-nucleotidase 1; dNT-15'(3')-deoxyribonucleotidase, cytosolic type; DNT1DNT-1; EC 3.1.3.-; P5N2; PN-I; PN-II; UMPH2DNT; uridine 5'-monophosphate phosphohydrolase 2; uridine 5-prime monophosphate hydrolase 2

Molecular Weight

Mass (kDA):
23.383 kDA

Genomic Context


Human

Location:	17q25.1
Sequence:	17; NC_000017.11 (75130225..75131965, complement)

Tissue Specificity

Detected in skeletal muscle, heart and pancreas.

Subcellular Localizations

Cytoplasm.

Diseases

Malignant Mesothelioma
Hereditary Diseases
Malignant Paraganglionic Neoplasm
Tissue Adhesions
Diabetes Mellitus
Insulin Resistance
Diabetes Mellitus, Non-insulin-dependent
Pleural Mesothelioma
Neoplasms
Diabetes Mellitus, Experimental

Obesity
Colorectal Neoplasms
Smith-magenis Syndrome
Mesothelioma

Pathways

Transport
Cell Adhesion
Lipid Oxidation
Gene Silencing
Cell Cycle
Dna Repair
Glucose Transport

Localization
Cytokinesis

PTMs

Phosphorylation

Oxidation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NT5C

References

PMID: 10681516 by Rampazzo C., et al. Mammalian 5'(3')-deoxyribonucleotidase, cDNA cloning, and overexpression of the enzyme in Escherichia coli and mammalian cells.

PMID: 12234672 by Rampazzo C., et al. Mouse cytosolic and mitochondrial deoxyribonucleotidases: cDNA cloning of the mitochondrial enzyme, gene structures, chromosomal mapping and comparison with the human orthologs.