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NSMF Antibodies
AND NSMF ELISA kits, NSMF Proteins
Many biological assays use antibodies to detect NSMF, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NSMF in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NSMF antibodies...
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NSMF Infographic by Boster Bio
All NSMF Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A08385-1
100 µg/vial
Cat # A08385-1
100 µg/vial
NSMF Overview
Facts about NMDA receptor synaptonuclear signaling and neuronal migration factor.
NMDA receptor synaptonuclear signaling and neuronal migration factor (NSMF)
Couples NMDA-sensitive glutamate receptor signaling to the nucleus and causes long-lasting changes in the cytoarchitecture of dendrites and spine synapse processes. Part of the cAMP response element-binding protein (CREB) shut-off signaling pathway.
Stimulates outgrowth of olfactory axons and migration of gonadotropin-releasing hormone (GnRH) and luteinizing-hormone-releasing hormone (LHRH) neuronal cells. .
Gene Information
| Human | |
|---|---|
| Gene Name: | NSMF |
| Uniprot: | Q6X4W1 |
| Entrez: | 26012 |
Family
| Belongs to: |
|---|
| NSMF family |
Alternative Names
NMDA receptor synaptonuclear signaling and neuronal migration factor
Molecular Weight
Mass (kDA):
60.143 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9q34.3 |
| Sequence: | 9; NC_000009.12 (137447570..137459334, complement) |
Tissue Specificity
Highly expressed in adult and fetal brain. Weakly expressed in heart, liver, spleen, testis, small intestine, skeletal muscle, peripheral white blood cells and kidney.
Subcellular Localizations
Nucleus. Nucleus envelope. Nucleus membrane. Nucleus matrix. Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein. Cell projection, dendrite. Cell junction, synapse. Cell junction, synapse, synaptosome. Cell junction, synapse, postsynaptic density. Membrane. Found on the outside of the luteinizing-hormone-releasing hormone (LHRH) cell membrane and axons projecting from the olfactory pit and epithelium. Associates with transcriptionally active chromatin regions. Detected at the nuclear membranes of CA1 neurons. Cortical cytoskeleton. Localized i
Diseases
- Hypogonadotropic hypogonadism 9 with or without anosmia (HH9)
PTMs
- Lipoprotein
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NSMF
bosterbio.com/bosterbio-gene-info-cards/NSMF
References
PMID: 15362570 by Miura K., et al. Characterization of the human nasal embryonic LHRH factor gene, NELF, and a mutation screening among 65 patients with idiopathic hypogonadotropic hypogonadism (IHH).
PMID: 20025934 by Xu N., et al. NELF is a nuclear protein involved in hypothalamic GnRH neuronal migration.