NRAP Antibodies

AND NRAP ELISA kits, NRAP Proteins

Many biological assays use antibodies to detect NRAP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NRAP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NRAP antibodies...

We validate the specificity of these antibodies to NRAP by testing them on tissues known to express NRAP positively and negatively. Browse below to find the NRAP antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NRAP Infographic by Boster Bio

All NRAP Products

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Anti-NRAP Antibody Picoband®

Human, Mouse, Rat

ELISA, WB

$370
Cat # A09321-1
100 µg/vial

NRAP Overview

Facts about Nebulin-related-anchoring protein.

NRAP 3D structure. Source: alphafold

Nebulin-related-anchoring protein (NRAP)

May be involved in anchoring the terminal actin filaments from the myofibril to the membrane and in transmitting tension from the myofibrils to the extracellular matrix. .

Gene Information

Human
Gene Name:	NRAP
Uniprot:	Q86VF7
Entrez:	4892

Family

Belongs to:

No superfamily

Alternative Names

nebulin-related anchoring protein; nebulin-related-anchoring protein; N-RAP

Molecular Weight

Mass (kDA):
197.074 kDA

Genomic Context


Human

Location:	10q25.3
Sequence:	10; NC_000010.11 (113588714..113664070, complement)

Tissue Specificity

Expressed in cardiac and skeletal muscle.

Subcellular Localizations

Localized at the myotendinous junction in skeletal muscle and at the intercalated disk in cardiac muscle.

Diseases

Cardiomyopathies
Myopathy
Neoplasms
Cardiomyopathy, Dilated
Hypertrophy
Cardiomyopathy, Familial Idiopathic
Neoplasm Metastasis
Congenital Muscular Dystrophy (disorder)
Spinal Cord Injuries
Melanoma
Spinal Injuries
Tumor Angiogenesis
Malignant Neoplasms

Contusions
Ventricular Dysfunction, Right
Ventricular Dysfunction, Left
Bacterial Infections
Rheumatoid Arthritis
Arthritis, Psoriatic
Ventricular Dysfunction

Interacting Proteins

ACTN2
CSRP3

Pathways

Myofibril Assembly
Localization
Ribosome Biogenesis
Heart Development
Rna Interference
Cell Adhesion
Cell-cell Signaling
Aging
Mitosis
Proteolysis
Synaptic Transmission
Regulation Of Gene Expression

Regeneration
Myotube Differentiation
Cell Cycle
Cell Death
Mating
Angiogenesis

PTMs

Phosphorylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NRAP

References

PMID: 12789664 by Mohiddin S.A., et al. Genomic organization, alternative splicing, and expression of human and mouse N-RAP, a nebulin-related LIM protein of striated muscle.

PMID: 9339382 by Luo G., et al. Mapping of the gene (NRAP) encoding N-RAP in the mouse and human genomes.