This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
1 Citations 1 Q&As
Facts about Nuclear receptor subfamily 4 group A member 1.
Binds the NGFI-B response element (NBRE) 5'- AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.
Human | |
---|---|
Gene Name: | NR4A1 |
Uniprot: | P22736 |
Entrez: | 3164 |
Belongs to: |
---|
nuclear hormone receptor family |
Early response protein NAK1; GFRP1ST-59; growth factor-inducible nuclear protein N10; HMR; HMRNP10; hormone receptor; MGC9485; N10; NAK1; NAK-1; NGFIB alpha; NGFI-B alpha; NGFIB; NR4A1; Nuclear hormone receptor NUR/77; nuclear receptor subfamily 4 group A member 1; nuclear receptor subfamily 4, group A, member 1; Nur77; Orphan nuclear receptor HMR; Orphan nuclear receptor TR3; steroid receptor TR3; Testicular receptor 3; TR3 orphan receptor; TR3
Mass (kDA):
64.463 kDA
Human | |
---|---|
Location: | 12q13.13 |
Sequence: | 12; NC_000012.12 (52022832..52059507) |
Fetal muscle and adult liver, brain and thyroid.
Nucleus. Cytoplasm. Mitochondrion. Nuclear export to the cytoplasm is XPO1-mediated and positively regulated by IFI27 (PubMed:22427340). Translocation to the mitochondrion upon interaction with RXRA and upon the presence of 9-cis retinoic acid (PubMed:17761950).
PMID: 2283997 by Nakai A., et al. A human early response gene homologous to murine nur77 and rat NGFI- B, and related to the nuclear receptor superfamily.
PMID: 2626032 by Chang C., et al. Isolation and characterization of human TR3 receptor: a member of steroid receptor superfamily.
*More publications can be found for each product on its corresponding product page