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- Table of Contents
Facts about Neuropeptide Y receptor type 4.
Receptor for neuropeptide Y and peptide YY.
The rank order of affinity of the receptor for pancreatic polypeptides is PP, PP (2-36) and [Ile-31, Gln-34] PP > [Pro-34] PYY > PYY and [Leu-31, Pro-34] NPY > NPY > PYY (3-36) and NPY (2-36) > PP (13- 36) > PP (31-36) > NPY free acid..
Human | |
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Gene Name: | NPY4R |
Uniprot: | P50391 |
Entrez: | 5540 |
Belongs to: |
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G-protein coupled receptor 1 family |
neuropeptide Y receptor type 4; NPY4R; NPY4RMGC116897; pancreatic polypeptide receptor 1NPY4-R; PP1Y4; PPYR1
Mass (kDA):
42.195 kDA
Human | |
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Location: | 10q11.22 |
Sequence: | 10; NC_000010.11 (46458548..46470694, complement) |
Highest levels found in brain, coronary artery and ileum. Low levels in pancreas and kidney. Detected in colon and small intestine.
Cell membrane; Multi-pass membrane protein.
PMID: 7592911 by Bard J.A., et al. Cloning and functional expression of a human Y4 subtype receptor for pancreatic polypeptide, neuropeptide Y, and peptide YY.
PMID: 7493937 by Lundell I., et al. Cloning of a human receptor of the NPY receptor family with high affinity for pancreatic polypeptide and peptide YY.