Neuroplastin Antibodies

AND Nptn ELISA kits, Neuroplastin Proteins

Many biological assays use antibodies to detect Neuroplastin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Neuroplastin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Neuroplastin antibodies...

We validate the specificity of these antibodies to Neuroplastin by testing them on tissues known to express Nptn positively and negatively. Browse below to find the Nptn antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Nptn Infographic by Boster Bio

All Nptn Products

Product

Figures

Specificity

Applications

Price

Anti-Neuroplastin NPTN Antibody

Human, Mouse, Rat

ELISA, IHC

$380
Cat # A08495
100ul

Anti-NPTN Mouse Monoclonal Antibody [Clone ID: OTI3C4]

Dog, Human, Monkey, Rat

IF, IHC, WB

$523
Cat # M08495
100 µl

Anti-NPTN Mouse Monoclonal Antibody [Clone ID: OTI2D4]

Dog, Human, Monkey, Mouse, Rat

IF, IHC, WB

$523
Cat # M08495-1
100 µl

NPTN (NM_017455) Human Over-expression Lysate

Human

$628
Cat # LS027020
100 µg

Nptn Overview

Facts about Neuroplastin.

Neuroplastin (Nptn)

Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation in hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway.

May play a role in synaptic plasticity (By similarity). .

Gene Information

Mouse
Gene Name:	Nptn
Uniprot:	P97300
Entrez:	20320

Family

Belongs to:

No superfamily

Alternative Names

AW554172; GP55; GP55Stromal cell-derived receptor 1; GP65SDR-1; GP66; MGC102805; Neuroplastin; np55; np65; NPTN; SDFR1; SDFR1DKFZp686L2477; SDR1; SDR1stromal cell derived factor receptor 1

Molecular Weight

Mass (kDA):
44.373 kDA

Genomic Context


Mouse

Location:	9\|9 B
Sequence:	9;

Tissue Specificity

Isoform 1 and isoform 2 are widely expressed with variable levels in brain. Isoform 1 is expressed in cerebellum and midbrain. Isoform 1 and isoform 2 are expressed in cerebral cortex, hipoccampus and striatum. Isoform 2 is more abundant in the cerebral cortex than isoform 1.

Diseases

Neoplasm Metastasis
Malignant Neoplasm Of Breast
Malignant Neoplasms
Neoplasms
Mammary Neoplasms
Cholangiocarcinoma
Pcp - Hallucinogen-related Disorder
Schizophrenia
Tissue Adhesions
Carcinoma

Tumor Angiogenesis
Nervousness
Lymphoma
Carcinoma Breast Stage Iv

Pathways

Tube Development
Cell Adhesion
Cell Proliferation
Immune Response
Angiogenesis
Neural Tube Development

Chromatin Remodeling

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Nptn

References

PMID: 8938438 by Shirozu M., et al. Characterization of novel secreted and membrane proteins isolated by the signal sequence trap method.

PMID: 28827723 by Korthals M., et al. A complex of Neuroplastin and Plasma Membrane Ca2+ ATPase controls T cell activation.