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- Table of Contents
3 Citations
3 Citations 5 Q&As
Facts about NADPH oxidase 1.
NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism, whereas NOH-1S doesn't contain an electron transport chain. .
Human | |
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Gene Name: | NOX1 |
Uniprot: | Q9Y5S8 |
Entrez: | 27035 |
Belongs to: |
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No superfamily |
EC 1.6.3; GP91-2; Mitogenic oxidase 1; MOX-1; MOX1NADH/NADPH mitogenic oxidase subunit P65-MOX; NADPH oxidase 1; NADPH oxidase homolog-1; NOH1; NOH1mitogenic oxidase (pyridine nucleotide-dependent superoxide-generating); NOH-1NADPH oxidase 1 variant NOH-1L; NOX1; NOX-1
Mass (kDA):
64.871 kDA
Human | |
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Location: | Xq22.1 |
Sequence: | X; NC_000023.11 (100843324..100874359, complement) |
NOH-1L is detected in colon, uterus, prostate, and colon carcinoma, but not in peripheral blood leukocytes. NOH- 1S is detected only in colon and colon carcinoma cells.
Cell projection, invadopodium membrane; Multi-pass membrane protein. Cell membrane.
PMID: 10485709 by Suh Y.-A., et al. Cell transformation by the superoxide-generating oxidase Mox1.
PMID: 10615049 by Banfi B., et al. A mammalian H+ channel, generated through alternative splicing of the NADPH oxidase homolog NOH-1.
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