Nucleolar protein 56 Antibodies

AND NOP56 ELISA kits, Nucleolar protein 56 Proteins

Many biological assays use antibodies to detect Nucleolar protein 56, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nucleolar protein 56 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nucleolar protein 56 antibodies...

We validate the specificity of these antibodies to Nucleolar protein 56 by testing them on tissues known to express NOP56 positively and negatively. Browse below to find the NOP56 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NOP56 Infographic by Boster Bio

All NOP56 Products

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Price

Anti-NOP56 Antibody

13 Q&As

Human, Mouse, Rat

IHC, WB

$399
Cat # A04335
100μl

NOL5A (NOP56) (NM_006392) Human Over-expression Lysate

Human

$628
Cat # LS010528
100 µg

NOP56 Overview

Facts about Nucleolar protein 56.

NOP56 3D structure. Source: alphafold

Nucleolar protein 56 (NOP56)

Involved from the early to middle stages of 60S ribosomal subunit biogenesis. Core part of box C/D small nucleolar ribonucleoprotein (snoRNP) particles.

Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs. .

Gene Information

Human
Gene Name:	NOP56
Uniprot:	O00567
Entrez:	10528

Family

Belongs to:

NOP5/NOP56 family

Alternative Names

NOL5A; NOP56 ribonucleoprotein homolog (yeast); nucleolar protein 56; nucleolar protein 5A (56kD with KKE/D repeat); nucleolar protein 5A (56kDa with KKE/D repeat); Nucleolar protein 5A

Molecular Weight

Mass (kDA):
66.05 kDA

Genomic Context


Human

Location:	20p13
Sequence:	20; NC_000020.11 (2652632..2658393)

Subcellular Localizations

Nucleus, nucleolus. Cytoplasm. Nucleus, nucleoplasm.

Diseases

Ataxia, Spinocerebellar
Ataxia
Atrophy
Trinucleotide Repeat Expansion
Sclerosis
Primary Lateral Sclerosis
Amyotrophic Lateral Sclerosis
Cerebellar Ataxia
Dysarthria
Nerve Degeneration
Muscular Fasciculation
Malignant Neoplasms

Truncal Ataxia
Limb Ataxias
Neurodegenerative Disorders
Cerebellar Dysarthria
Motor Neuron Disease
Fasciculation Of Tongue

Pathways

Methylation
Ribosome Biogenesis
Localization
Rrna Processing
Transport
Cell Cycle
Rrna Methylation
Rrna Modification
Rna Processing
Mitosis
Snorna Processing
Reflex
Mismatch Repair

Cell Division
Drug Resistance
Telophase
Rna Transport
S Phase
Cell Differentiation
Epithelial Cell Differentiation

PTMs

Methylation

Sumoylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NOP56

References

PMID: 9372940 by Gautier T., et al. Nucleolar KKE/D repeat proteins Nop56p and Nop58p interact with Nop1p and are required for ribosome biogenesis.

PMID: 12417735 by Watkins N.J., et al. Conserved stem II of the box C/D motif is essential for nucleolar localization and is required, along with the 15.5K protein, for the hierarchical assembly of the box C/D snoRNP.