Noggin Antibodies

AND NOG ELISA kits, Noggin Proteins

Many biological assays use antibodies to detect Noggin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Noggin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Noggin antibodies...

We validate the specificity of these antibodies to Noggin by testing them on tissues known to express NOG positively and negatively. Browse below to find the NOG antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NOG Infographic by Boster Bio

All NOG Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Noggin Antibody Picoband®

1 Citations 1 Q&As

Human

ELISA, IHC, WB

$370
Cat # A04448-1
100 μg/vial

Noggin Mouse Recombinant Protein

Mouse

$250
Cat # PROTP97466
5ug, 20ug, 1mg

Anti-Noggin (NOG) Mouse Monoclonal Antibody [Clone ID: OTI1C1]

Human, Mouse, Rat

IF, IHC, WB

$523
Cat # M04448
100 µl

Noggin (NOG) (NM_005450) Human Over-expression Lysate

Human

$628
Cat # LS009241
100 µg

Human recombinant Noggin protein, AF

Human

Cell Culture

$77
Cat # PROTQ13253-6
5ug,20ug,100ug

Mouse recombinant Noggin protein, AF

Mouse

Cell Culture

$77
Cat # PROTP97466-2
5ug,20ug,100ug

NOG Overview

Facts about Noggin.

NOG 3D structure. Source: alphafold

Noggin (NOG)

Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. Essential for cartilage morphogenesis and joint formation.

Inhibits chondrocyte differentiation through its interaction with GDF5 and, likely, GDF6 (PubMed:21976273, PubMed:26643732). .

Gene Information

Human
Gene Name:	NOG
Uniprot:	Q13253
Entrez:	9241

Family

Belongs to:

noggin family

Alternative Names

NOG; Noggin; SYM1; symphalangism 1 (proximal); synostoses (multiple) syndrome 1; SYNS1; SYNS1A

Molecular Weight

Mass (kDA):
25.774 kDA

Genomic Context


Human

Location:	17q22
Sequence:	17; NC_000017.11 (56593699..56595611)

Subcellular Localizations

Secreted.

Diseases

Immunologic Deficiency Syndromes
Neoplasms
Malignant Neoplasms
Syndactyly
Congenital Abnormal Synostosis
Severe Combined Immunodeficiency
Conductive Hearing Loss
Neoplasm Metastasis
Ankylosis
Congenital Combined Immunodeficiency
Lymphoma
Hyperopia

Congenital Abnormality
Hiv Infections
Malignant Paraganglionic Neoplasm
Brachydactyly
Leukemia
Tissue Adhesions

Interacting Proteins

BMP2

Pathways

Pathogenesis
Cell Proliferation
Cell Growth
Secretion
Cell Differentiation
Ossification
Regeneration
Cell Cycle
Cell Death
Immune Response
Gastrulation
Cell Development
Cell Migration

Tissue Development
Segmentation
Delamination
Stem Cell Differentiation
Translation
Paracrine Signaling
Antibody-dependent Cellular Cytotoxicity

PTMs

Phosphorylation
Methylation
Dephosphorylation

Demethylation
Carboxylation
Myristoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NOG

References

PMID: 7666191 by Valenzuela D.M., et al. Identification of mammalian noggin and its expression in the adult nervous system.

PMID: 21976273 by Schwaerzer G.K., et al. New insights into the molecular mechanism of multiple synostoses syndrome (SYNS): mutation within the GDF5 knuckle epitope causes noggin-resistance.

1 Publications of Boster Noggin Antibodies & ELISA Kits

PubMed ID: 21573506, Expression of NANOG in human gliomas and its relationship with undifferentiated ...

*More publications can be found for each product on its corresponding product page