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- Table of Contents
Facts about Nocturnin.
Exerts a rhythmic post-transcriptional control of genes necessary for metabolic functions such as nutrient absorption, glucose/insulin sensitivity, lipid metabolism, adipogenesis, inflammation and osteogenesis. Plays an essential role in favoring adipogenesis over osteoblastogenesis and functions as a key regulator of the adipogenesis/osteogenesis equilibrium.
Mouse | |
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Gene Name: | Noct |
Uniprot: | O35710 |
Entrez: | 12457 |
Belongs to: |
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CCR4/nocturin family |
Nocturnin
Mass (kDA):
48.301 kDA
Mouse | |
---|---|
Location: | 3|3 C |
Sequence: | 3; |
Highly expressed in the differentiated adipocyte (at protein level). Ubiquitous.
PMID: 9038221 by Puech A., et al. Characterization of two age-induced intracisternal A-particle-related transcripts in the mouse liver. Transcriptional read-through into an open reading frame with similarities to the yeast ccr4 transcription factor.
PMID: 10521507 by Dupressoir A., et al. Characterization of a mammalian gene related to the yeast CCR4 general transcription factor and revealed by transposon insertion.