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- Table of Contents
Facts about Nicotinamide riboside kinase 2.
Involved in the regulation of PXN in the protein level and of PXN tyrosine phosphorylation. May play a role in the regulation of terminal myogenesis.
Human | |
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Gene Name: | NMRK2 |
Uniprot: | Q9NPI5 |
Entrez: | 27231 |
Belongs to: |
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uridine kinase family |
EC 2.7.1.22; EC 2.7.1.n4; integrin beta 1 binding protein 3; Integrin beta-1-binding protein 3; MGC126624; MIBPNRK 2; Muscle integrin-binding protein; muscle-specific beta 1 integrin binding protein; nicotinamide riboside kinase 2; Nicotinic acid riboside kinase 2; NmR-K 2; NRK2RNK 2; Ribosylnicotinamide kinase 2; Ribosylnicotinic acid kinase 2
Mass (kDA):
26.046 kDA
Human | |
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Location: | 19p13.3 |
Sequence: | 19; NC_000019.10 (3933103..3942416) |
Predominantly expressed in skeletal muscle and, at a much lower level, in the heart (at protein level). No expression in brain, kidney, liver, lung, pancreas nor placenta.
PMID: 10613898 by Li J., et al. A novel muscle-specific beta 1 integrin binding protein (MIBP) that modulates myogenic differentiation.
PMID: 15137942 by Bieganowski P., et al. Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans.