Neugrin Antibodies

AND NGRN ELISA kits, Neugrin Proteins

Many biological assays use antibodies to detect Neugrin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Neugrin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Neugrin antibodies...

We validate the specificity of these antibodies to Neugrin by testing them on tissues known to express NGRN positively and negatively. Browse below to find the NGRN antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NGRN Infographic by Boster Bio

All NGRN Products

Product

Figures

Specificity

Applications

Price

Anti-Neugrin NGRN Antibody

Human

ELISA, WB

$380
Cat # A12695
100ul

Neugrin (NGRN) (NM_016645) Human Recombinant Protein

$1249
Cat # PROTQ9NPE2
20 µg

Neugrin (NGRN) (NM_016645) Human Over-expression Lysate

Human

$628
Cat # LS051335
100 µg

NGRN Overview

Facts about Neugrin.

NGRN 3D structure. Source: alphafold

Neugrin (NGRN)

Plays an important role in mitochondrial ribosome biogenesis. As a part of a functional protein-RNA module, composed of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA prosperity and is needed for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.

Gene Information

Human
Gene Name:	NGRN
Uniprot:	Q9NPE2
Entrez:	51335

Family

Belongs to:

neugrin family

Alternative Names

DSC92; FI58G; Mesenchymal stem cell protein DSC92; Neugrin; neugrin, neurite outgrowth associated; neurite outgrowth associated protein; Neurite outgrowth-associated protein; NGRN; Spinal cord-derived protein FI58G

Molecular Weight

Mass (kDA):
32.408 kDA

Genomic Context


Human

Location:	15q26.1
Sequence:	15; NC_000015.10 (90265663..90272211)

Tissue Specificity

Expressed at high levels in heart, brain and skeletal muscle. In brain, mainly expressed in neurons rather than glial cells.

Subcellular Localizations

Nucleus. Secreted. Mitochondrion membrane.

Diseases

Learning Disorders
Nervousness
Impairment (finding)
Neurodegenerative Disorders
Memory Impairment
Impaired Cognition

Alzheimer's Disease

Pathways

System Development
Nervous System Development
Cell Differentiation
Immune Response
Cell Growth

PTMs

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NGRN

References

PMID: 11118320 by Ishigaki S., et al. Two novel genes, human neugrin and mouse m-neugrin, are upregulated with neuronal differentiation in neuroblastoma cells.

PMID: 27667664 by Arroyo J.D., et al. A Genome-wide CRISPR Death Screen Identifies Genes Essential for Oxidative Phosphorylation.