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- Table of Contents
Facts about NF-kappa-B inhibitor-like protein 1.
Contributes to the negative regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli. .
Human | |
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Gene Name: | NFKBIL1 |
Uniprot: | Q9UBC1 |
Entrez: | 4795 |
Belongs to: |
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No superfamily |
IkappaBL; I-kappa-B-like protein; IKBLikappaBL; Inhibitor of kappa B-like protein; LST1; NF-kappa-B inhibitor-like protein 1; nuclear factor of kappa light polypeptide gene enhancer in B-cellsinhibitor-like 1NFKBIL
Mass (kDA):
43.204 kDA
Human | |
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Location: | 6p21.33 |
Sequence: | 6; NC_000006.12 (31546851..31558829) |
Detected in different cell types including monocytes, T-cells, B-cells and hepatocytes.
Nucleus. Nuclear localization with a speckled expression pattern in some cells. Colocalizes with CACTIN in the nucleus.
PMID: 8081366 by Albertella M.R., et al. Characterization of a novel gene in the human major histocompatibility complex that encodes a potential new member of the I kappa B family of proteins.
PMID: 9480751 by Shiina T., et al. Nucleotide sequencing analysis of the 146-kilobase segment around the IkBL and MICA genes at the centromeric end of the HLA class I region.