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NF-kappa-B inhibitor beta Antibodies
AND NFKBIB ELISA kits, NF-kappa-B inhibitor beta Proteins
Many biological assays use antibodies to detect NF-kappa-B inhibitor beta, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NF-kappa-B inhibitor beta in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NF-kappa-B inhibitor beta antibodies...
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NFKBIB Infographic by Boster Bio
All NFKBIB Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IHC, WB
$370
Cat # PB9292
100 μg/vial
Cat # PB9292
100 μg/vial
Human, Mouse
ELISA
$480
Cat # EKC1312
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1312
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC1944
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC1944
1 kit, containing two 96-well plates and all necessary reagents
Human
ELISA
$540
Cat # EKC2041
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2041
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A05766S23
100ul
Cat # A05766S23
100ul
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A05766-1
100 μg/vial
Cat # A05766-1
100 μg/vial
NFKBIB Overview
Facts about NF-kappa-B inhibitor beta.
NF-kappa-B inhibitor beta (NFKBIB)
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation can bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA- dependent inactivation.
Association with inhibitor kappa B- interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation making it more resistant to degradation, describing its slower degradation. .
Gene Information
| Human | |
|---|---|
| Gene Name: | NFKBIB |
| Uniprot: | Q15653 |
| Entrez: | 4793 |
Family
| Belongs to: |
|---|
| NF-kappa-B inhibitor family |
Alternative Names
beta; IkappaBbeta; I-kappa-B-beta; ikB-B; IkBbeta; IkB-beta; IKBBikB-beta; NF-kappa-B inhibitor beta; NF-kappa-BIB; NFKBIB; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor; Thyroid receptor-interacting protein 9; TR-interacting protein 9; TRIP-9; TRIP9ikappaBbeta
Molecular Weight
Mass (kDA):
37.771 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19q13.2 |
| Sequence: | 19; NC_000019.10 (38899503..38908894) |
Tissue Specificity
Expressed in all tissues examined.
Subcellular Localizations
Cytoplasm. Nucleus.
Diseases
- Inflammation
- Malignant Neoplasms
- Liver Diseases
- Neoplasm Metastasis
- Infarction
- Malignant Neoplasm Of Breast
- Communicable Diseases
- Endometrial Polyp
- Lung Diseases
- Inflammatory Breast Carcinoma
- Inflammatory Response
- Chronic Obstructive Airway Disease
Interacting Proteins
- FBXW11
- RELA
- VPS52
Pathways
- Response To Oxidative Stress
- Cell Proliferation
- Cellular Localization
- Immune Response
- Regulation Of Gene Expression
- Angiogenesis
- Pathogenesis
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NFKBIB
bosterbio.com/bosterbio-gene-info-cards/NFKBIB
References
PMID: 7776974 by Lee J.W., et al. Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.
PMID: 8816457 by Suyang H., et al. Role of unphosphorylated, newly synthesized IkappaB beta in persistent activation of NF-kappaB.