NFE2L1 Antibodies

AND NFE2L1 ELISA kits, NFE2L1 Proteins

Many biological assays use antibodies to detect NFE2L1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NFE2L1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NFE2L1 antibodies...

We validate the specificity of these antibodies to NFE2L1 by testing them on tissues known to express NFE2L1 positively and negatively. Browse below to find the NFE2L1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NFE2L1 Infographic by Boster Bio

All NFE2L1 Products

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Anti-NFE2L1 monoclonal Antibody

Human

$482
Cat # M06662
100ul

Anti-NF2L1 NFE2L1 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A06662
100ul

NFE2L1 Overview

Facts about Endoplasmic reticulum membrane sensor NFE2L1.

NFE2L1 3D structure. Source: alphafold

Endoplasmic reticulum membrane sensor NFE2L1 (NFE2L1)

Endoplasmic reticulum membrane sensor NFE2L1: Endoplasmic reticulum membrane sensor that translocates into the nucleus in response to various stresses to act as a transcription factor (PubMed:20932482, PubMed:24448410). Constitutes a precursor of the transcription factor NRF1 (By similarity).

Willing to detect various cellular stresses, such as cholesterol surplus, oxidative stress or proteasome inhibition (PubMed:20932482). In response to pressure, it is released from the endoplasmic reticulum membrane following cleavage by the protease DDI2 and translocates into the nucleus to form the transcription factor NRF1 (By similarity).

Gene Information

Human
Gene Name:	NFE2L1
Uniprot:	Q14494
Entrez:	4779

Family

Belongs to:

bZIP family

Alternative Names

FLJ00380; HBZ17; LCR-F1; Locus control region-factor 1; NF-E2-related factor 1; NFE2-related factor 1; NRF1TCF11; nuclear factor (erythroid-derived 2)-like 1; nuclear factor erythroid 2-related factor 1; Nuclear factor, erythroid derived 2, like 1; TCF-11; transcription factor 11 (basic leucine zipper type); Transcription factor 11; Transcription factor HBZ17; Transcription factor LCR-F1

Molecular Weight

Mass (kDA):
84.704 kDA

Genomic Context


Human

Location:	17q21.32
Sequence:	17; NC_000017.11 (48048359..48061545)

Subcellular Localizations

[Endoplasmic reticulum membrane sensor NFE2L1]: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein. In normal conditions, probably has a single-pass type II membrane protein topology, with the DNA-binding domain facing the endoplasmic reticulum lumen (PubMed:24448410). Following cellular stress, it is rapidly and efficiently retrotranslocated to the cytosolic side of the membrane, a process dependent on p97/VCP, to have a single-pass type III membrane protein topology with the major part of the protein fac