Nebulin Antibodies

AND NEB ELISA kits, Nebulin Proteins

Many biological assays use antibodies to detect Nebulin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nebulin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nebulin antibodies...

We validate the specificity of these antibodies to Nebulin by testing them on tissues known to express NEB positively and negatively. Browse below to find the NEB antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NEB Infographic by Boster Bio

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Anti-Nebulin Antibody (Monoclonal, NB2)

1 Citations 2 Q&As

Chicken

$370
Cat # MA1069
100 μg/vial

NEB Overview

Facts about Nebulin.

Nebulin (NEB)

This giant muscle protein may be involved in maintaining the structural integrity of sarcomeres and the membrane system connected with the myofibrils. Binds and stabilize F-actin.

Gene Information

Human
Gene Name:	NEB
Uniprot:	P20929
Entrez:	4703

Family

Belongs to:

No superfamily

Alternative Names

DKFZp686C1456; FLJ11505; FLJ36536; FLJ39568; FLJ39584; NEB177D; nebulin; NEM2

Molecular Weight

Mass (kDA):
772.914 kDA

Genomic Context


Human

Location:	2q23.3
Sequence:	2; NC_000002.12 (151485334..151734487, complement)

Tissue Specificity

Muscle specific. Located in the thin filament of striated muscle.

Subcellular Localizations

Cytoplasm, myofibril, sarcomere. Cytoplasm, cytoskeleton.

Diseases

Myopathy
Hypoxia
Myopathies, Nemaline
Hyperplasia
Weakness
Lung Diseases
Neoplasms
Anoxia
Congenital Myopathy (disorder)
Nervousness
Carcinoma, Neuroendocrine
Asthma
Muscle Weakness

Hypertensive Disease
Lung Diseases, Obstructive
Malignant Neoplasm Of Lung
Pulmonary Hypertension
Mastitis
Carcinoma
Fibrosis

Interacting Proteins

ACO1
DOCK9
DYSF
KLHL41
MYPN

SOS1
SVIL
TTN

Pathways

Innervation
Mitosis
Lactation
Cell Cycle
Localization
Exocytosis
Lung Development
Anaphase
Pathogenesis
Methylation
Secretion
Interphase
Prophase

Metaphase
Ovulation
Transport
Fertilization
Immune Response
Parturition
Spindle Assembly

PTMs

Phosphorylation
Oxidation
Cleavage
Nitration

Amidation
Decarboxylation
Methylation
Geranylgeranylation

Research Areas

Cell Biology
Cellular Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NEB

References

PMID: 7739042 by Labeit S., et al. The complete primary structure of human nebulin and its correlation to muscle structure.

PMID: 1682316 by Jin J.P., et al. Cloning, expression, and protein interaction of human nebulin fragments composed of varying numbers of sequence modules.

1 Publications of Boster Nebulin Antibodies & ELISA Kits

PubMed ID: 24345394, Li X, Ni M, Zhang C, Ma W, Zhang Y. Rna. 2014 Feb;20(2):252-9. Doi: 10.1261/Rna....

*More publications can be found for each product on its corresponding product page