NDC80 Antibodies

AND NDC80 ELISA kits, NDC80 Proteins

Many biological assays use antibodies to detect NDC80, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NDC80 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NDC80 antibodies...

We validate the specificity of these antibodies to NDC80 by testing them on tissues known to express NDC80 positively and negatively. Browse below to find the NDC80 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NDC80 Infographic by Boster Bio

All NDC80 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-KNTC2 NDC80 Antibody

Human, Mouse

IF, WB

$360
Cat # A01731-1
100 µl

Anti-HEC1 NDC80 Monoclonal Antibody

4 Q&As

Human, Mouse, Rat

IP, WB

$370
Cat # M01731
100 μl

KNTC2 Colorimetric Cell-Based ELISA

Human, Mouse

ELISA

$480
Cat # EKC1623
1 kit, containing one 96-well plate and all necessary reagents

Anti-HEC1/HEC/NDC80 Antibody Picoband®

1 Q&As

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A01731-2
100 μg/vial

Anti-NDC80 Antibody (C-Term)

Human

$299
Cat # M01731-1
50 µl

HEC1 (NDC80) (NM_006101) Human Over-expression Lysate

Human

$628
Cat # LS010403
100 µg

NDC80 Overview

Facts about Kinetochore protein NDC80 homolog.

NDC80 3D structure. Source: alphafold

Kinetochore protein NDC80 homolog (NDC80)

Acts as a component of the essential kinetochore- related NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:9315664, PubMed:12351790, PubMed:14654001, PubMed:14699129, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:16732327). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:15548592).

The NDC80 complex synergistically enhances the affinity of this SKA1 complicated for microtubules and might allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020). Plays a role in chromosome congression and is essential for the end-on attachment of the kinetochores to spindle microtubules (PubMed:25743205, PubMed:23891108).

Gene Information

Human
Gene Name:	NDC80
Uniprot:	O14777
Entrez:	10403

Family

Belongs to:

NDC80/HEC1 family

Alternative Names

HEC1KNTC2; HECRetinoblastoma-associated protein HEC; Highly expressed in cancer protein; highly expressed in cancer, rich in leucine heptad repeats (yeast); highly expressed in cancer, rich in leucine heptad repeats; hsHec1; hsNDC80; kinetochore associated 2; Kinetochore protein Hec1; kinetochore protein NDC80 homolog; Kinetochore-associated protein 2; NDC80 homolog, kinetochore complex component (S. cerevisiae); TID3

Molecular Weight

Mass (kDA):
73.913 kDA

Genomic Context


Human

Location:	18p11.32
Sequence:	18; NC_000018.10 (2571557..2616635)

Subcellular Localizations

Nucleus. Chromosome, centromere, kinetochore. Localizes to kinetochores from late prophase to anaphase. Localizes specifically to the outer plate of the kinetochore.