NCF4 Antibodies

AND NCF4 ELISA kits, NCF4 Proteins

Many biological assays use antibodies to detect NCF4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NCF4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NCF4 antibodies...

We validate the specificity of these antibodies to NCF4 by testing them on tissues known to express NCF4 positively and negatively. Browse below to find the NCF4 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NCF4 Infographic by Boster Bio

All NCF4 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Phospho p40 phox (Thr154) NCF4 Antibody

3 Q&As

Human, Mouse

ELISA, IHC-P, IF (paraffin)

$335
Cat # P04208
100ul

Anti-p40-phox (R149) NCF4 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A04208
100ul

Anti-Phospho-p40-phox (T154) NCF4 Antibody

Human, Mouse

ELISA, IHC

$380
Cat # A04208T154
100ul

NCF4 (NM_000631) Human Recombinant Protein

$813
Cat # PROTQ15080
20 µg

Anti-NCF4 Mouse Monoclonal Antibody [Clone ID: OTI4B5]

Human, Mouse, Rat

IHC, WB

$523
Cat # M04208
100 µl

Anti-NCF4 Rabbit Monoclonal Antibody

Human

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M04208-1
100 μl/vial

NCF4 Overview

Facts about Neutrophil cytosol factor 4.

NCF4 3D structure. Source: alphafold

Neutrophil cytosol factor 4 (NCF4)

Component of the NADPH-oxidase, a multicomponent enzyme system responsible for the oxidative burst in which electrons are transported from NADPH to molecular oxygen, generating reactive oxidant intermediates. It may be important for the assembly and/or activation of the NADPH-oxidase complex.

Gene Information

Human
Gene Name:	NCF4
Uniprot:	Q15080
Entrez:	4689

Family

Belongs to:

No superfamily

Alternative Names

MGC3810; NCF; NCF-4; neutrophil cytosol factor 4; neutrophil cytosolic factor 4 (40kD); neutrophil cytosolic factor 4, 40kDa; Neutrophil NADPH oxidase factor 4; p40phox; p40-phox; SH3 and PX domain-containing protein 4; SH3PXD4P40PHOX

Molecular Weight

Mass (kDA):
39.032 kDA

Genomic Context


Human

Location:	22q12.3
Sequence:	22; NC_000022.11 (36860988..36878017)

Tissue Specificity

Expression is restricted to hematopoietic cells.

Subcellular Localizations

Cytoplasm, cytosol. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Membrane; Peripheral membrane protein.

Diseases

Crohn Disease
Inflammatory Bowel Diseases
Intestinal Diseases
Colitis
Granulomatous Disease, Chronic
Inflammation
Granulomatous Disorder
Carcinoma
Ulcer
Malignant Neoplasms
Neoplasms
Lymphoma
Cardiotoxicity

Ileal Diseases
Malignant Squamous Cell Neoplasm
Ulcerative Colitis
Cholangiocarcinoma
Immunologic Deficiency Syndromes
Chronic Inflammation
Crohn's Disease Of Large Bowel

Interacting Proteins

NCF1
NCF2

Pathways

Localization
Phagocytosis
Autophagy
Pathogenesis
Secretion
Transport
Reproductive Process
Neutrophil Chemotaxis
Cytokine Secretion
Pigmentation
Respiratory Burst
Sporulation
Virulence

Cell Maturation
Senescence
Replicative Senescence
Chemotaxis
Doxorubicin Transport
Granuloma Formation
Tissue Homeostasis

PTMs

Phosphorylation

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NCF4

References

PMID: 8280052 by Wientjes F.B., et al. p40phox, a third cytosolic component of the activation complex of the NADPH oxidase to contain src homology 3 domains.

PMID: 8839867 by Zhan S., et al. Genomic structure, chromosomal localization, start of transcription, and tissue expression of the human p40-phox, a new component of the nicotinamide adenine dinucleotide phosphate-oxidase complex.