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- Table of Contents
Facts about Neuroblastoma-amplified sequence.
Human | |
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Gene Name: | NBAS |
Uniprot: | A2RRP1 |
Entrez: | 51594 |
Belongs to: |
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No superfamily |
DKFZp586G1219; EC 1.1.1.94; EC 1.2.1.59; FLJ40407; NAG/BC035112 fusion; NAG/FAM49A fusion; NAGneuroblastoma-amplified protein; neuroblastoma amplified sequence; Neuroblastoma-amplified gene protein; neuroblastoma-amplified sequence
Mass (kDA):
268.571 kDA
Human | |
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Location: | 2p24.3 |
Sequence: | 2; NC_000002.12 (14998067..15561344, complement) |
Broadly expressed, with highest levels in heart and skeletal muscle, and lowest levels in liver, small intestine and thymus. Well expressed in retinal ganglion cells, epidermal skin cells, and leukocytes. Up-regulated together with N-myc in some neuroblastoma cell lines.
Cytoplasm. Endoplasmic reticulum. Endoplasmic reticulum membrane; Peripheral membrane protein.
PMID: 12706883 by Scott D.K., et al. The neuroblastoma amplified gene, NAG: genomic structure and characterisation of the 7.3 kb transcript predominantly expressed in neuroblastoma.
PMID: 9926938 by Wimmer K., et al. Co-amplification of a novel gene, NAG, with the N-myc gene in neuroblastoma.