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NGFI-A-binding protein 2 Antibodies
AND NAB2 ELISA kits, NGFI-A-binding protein 2 Proteins
Many biological assays use antibodies to detect NGFI-A-binding protein 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NGFI-A-binding protein 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NGFI-A-binding protein 2 antibodies...
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NAB2 Infographic by Boster Bio
All NAB2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
ELISA
$480
Cat # EKC1830
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1830
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
IHC, WB
$523
Cat # M02873
100 µl
Cat # M02873
100 µl
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A02873-3
100 μg/vial
Cat # A02873-3
100 μg/vial
NAB2 Overview
Facts about NGFI-A-binding protein 2.
NGFI-A-binding protein 2 (NAB2)
Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Isoform 2 lacks repression ability (By similarity).
. .
Gene Information
| Human | |
|---|---|
| Gene Name: | NAB2 |
| Uniprot: | Q15742 |
| Entrez: | 4665 |
Family
| Belongs to: |
|---|
| NAB family |
Alternative Names
EGR-1-binding protein 2; MADEREGR1 binding protein 2; Melanoma-associated delayed early response protein; MGC75085; NGFI-A binding protein 2 (EGR1 binding protein 2); NGFI-A-binding protein 2; Protein MADER
Molecular Weight
Mass (kDA):
56.594 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q13.3 |
| Sequence: | 12; NC_000012.12 (57089114..57095476) |
Tissue Specificity
Widely expressed at low levels. Highly expressed in melanoma cell lines.
Subcellular Localizations
Nucleus. Isoform 2 is not localized to the nucleus.
Diseases
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Malignant Neoplasm Of Prostate
- Inflammation
- Nervousness
- Melanoma
- Tumor Angiogenesis
- Prostatic Neoplasms
- Peripheral Neuropathy
- Fibrosis
- Congenital Hypomyelinating Neuropathy
Interacting Proteins
- AES
- CWF19L2
- GCC1
- JAKMIP2
- KRTAP10-8
- LENG1
- MCM7
- MORF4L1
- NEDD9
- NME7
Pathways
- Nuclear Export
- Localization
- Myelination
- Translation
- Transport
- Nuclear Import
- Pathogenesis
- Angiogenesis
- Rna Processing
- Nuclear Transport
- Chromatin Remodeling
- Cell Proliferation
- Hindbrain Development
PTMs
- Phosphorylation
- Methylation
- Cleavage
Research Areas
- Neuroscience
- Transcription Factors and Regulators
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NAB2
bosterbio.com/bosterbio-gene-info-cards/NAB2
References
PMID: 8668170 by Svaren J., et al. NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli.
PMID: 8649813 by Kirsch K.H., et al. Mader: a novel nuclear protein over expressed in human melanomas.