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NEDD4-binding protein 1 Antibodies
AND N4BP1 ELISA kits, NEDD4-binding protein 1 Proteins
Many biological assays use antibodies to detect NEDD4-binding protein 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NEDD4-binding protein 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NEDD4-binding protein 1 antibodies...
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N4BP1 Infographic by Boster Bio
All N4BP1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, IF, ICC, WB
$449
Cat # A12575-1
0.1 mg
Cat # A12575-1
0.1 mg
Human
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A12575-3
100 µg/vial
Cat # A12575-3
100 µg/vial
N4BP1 Overview
Facts about NEDD4-binding protein 1.
NEDD4-binding protein 1 (N4BP1)
Inhibitor of the E3 ubiquitin-protein ligase ITCH.
Acts by interacting with the next WW domain of ITCH, leading to compete with ITCH's substrates and impairing ubiquitination of substrates (By similarity).. .
Gene Information
| Human | |
|---|---|
| Gene Name: | N4BP1 |
| Uniprot: | O75113 |
| Entrez: | 9683 |
Family
| Belongs to: |
|---|
| N4BP1 family |
Alternative Names
FLJ31821; KIAA0615; MGC176730; NEDD4 binding protein 1; NEDD4-binding protein 1
Molecular Weight
Mass (kDA):
100.379 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16q12.1 |
| Sequence: | 16; NC_000016.10 (48538726..48610214, complement) |
Tissue Specificity
Detected in heart, lung, brain, liver, skeletal muscle, pancreas, kidney, spleen, testis and ovary.
Subcellular Localizations
Nucleus, nucleolus. Nucleus, PML body. Primarily localizes to the nucleolus. Also localizes to the PML nuclear bodies, when desumoylated (By similarity).
Diseases
- Malignant Neoplasms
- Neoplasms
- Cell Invasion
- Malignant Neoplasm Of Prostate
- Neoplasm Metastasis
- Tumor Progression
- Leukemia
Interacting Proteins
- Azi2
- ITCH
Pathways
- Cell Migration
- Cell Death
- Trna Processing
- Proteolysis
PTMs
- Sumoylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/N4BP1
bosterbio.com/bosterbio-gene-info-cards/N4BP1
References
PMID: 9734811 by Ishikawa K., et al. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.
PMID: 15616553 by Martin J., et al. The sequence and analysis of duplication-rich human chromosome 16.