MARCKS-related protein Antibodies

AND Marcksl1 ELISA kits, MARCKS-related protein Proteins

Many biological assays use antibodies to detect MARCKS-related protein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MARCKS-related protein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MARCKS-related protein antibodies...

We validate the specificity of these antibodies to MARCKS-related protein by testing them on tissues known to express Marcksl1 positively and negatively. Browse below to find the Marcksl1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Marcksl1 Infographic by Boster Bio

All Marcksl1 Products

Product

Figures

Specificity

Applications

Price

Anti-MARCKS (Myristoylated Alanine Rich C Kinase Substrate) Antibody

1 Q&As

Human

IF, ICC, WB

$299
Cat # M04133
100ul

Human, Mouse, Rat

$405
Cat # A06798
100ul

Human MARCKSL1 Recombinant Protein

SDS-PAGE

$250
Cat # PROTP49006
Starting from 4ug

MARCKS like protein (MARCKSL1) (NM_023009) Human Over-expression Lysate

Human

$628
Cat # LS065108
100 µg

Marcksl1 Overview

Facts about MARCKS-related protein.

MARCKS-related protein (Marcksl1)

Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration.

When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, such as neuronal migration. May also affect cancer cell migration.

Gene Information

Mouse
Gene Name:	Marcksl1
Uniprot:	P28667
Entrez:	17357

Family

Belongs to:

MARCKS family

Alternative Names

F52; MacMARCKS; mac-MARCKS; Macrophage myristoylated alanine-rich C kinase substrate; MARCKS-like 1; MARCKS-like protein 1; MARCKS-related protein; MLP1; MLPMARCKS-like protein; MRPMACMARCKS

Molecular Weight

Mass (kDA):
20.165 kDA

Genomic Context


Mouse

Location:	4 D2.2\|4 63.26 cM
Sequence:	4;

Tissue Specificity

Expressed at high levels in brain cortex and hippocampus (at protein level), including dentate gyrus, anterior olfactory nucleus, primary olfactory cortex, entorhinal cortex, medial preoptic area and dorsomedial hypothalamic nucleus. Expressed in neuronal cells (at protein level). Also detected in the retina. Up-regulated in a wide variety of cancers.

Diseases

Tissue Adhesions
Malignant Neoplasms
Neoplasm Metastasis
Neoplasms
Nervousness
Malignant Neoplasm Of Prostate
Inflammation
Congenital Abnormality
Nerve Degeneration
Spina Bifida
Prostatic Neoplasms
Malignant Neoplasm Of Breast

Endometrial Polyp
Carotid Artery Injuries
Inflammatory Response
Carcinoma
Eye Abnormalities
Edema

Pathways

Integrin Activation
Secretion
Phagocytosis
Cell Adhesion
Brain Development
Localization
Cell Migration
Exocytosis
Regeneration
Protein Phosphorylation
Neural Tube Closure
Gene Silencing
Tube Formation

Cytokine Secretion
Muscle Contraction
Serotonin Uptake
Nuclear Export
Inflammatory Response
Chemotaxis
Cell Motility

PTMs

Myristoylation
Phosphorylation

Cleavage
Acetylation

Acylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Marcksl1

References

PMID: 1864362 by Umekage T., et al. A mouse brain cDNA encodes a novel protein with the protein kinase C phosphorylation site domain common to MARCKS.

PMID: 1516135 by Li J., et al. MacMARCKS, a novel member of the MARCKS family of protein kinase C substrates.