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- Table of Contents
Facts about Unconventional myosin-IXa.
Regulates Rho activity in neurons, has a role in the regulation of neuronal morphology and function (By similarity). .
Human | |
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Gene Name: | MYO9A |
Uniprot: | B2RTY4 |
Entrez: | 4649 |
Belongs to: |
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TRAFAC class myosin-kinesin ATPase superfamily |
FLJ11061; FLJ13244; MGC71859; MYO9A variant protein; myosin IXA; myosin-IXa; MYR7; Unconventional myosin-9a
Mass (kDA):
292.706 kDA
Human | |
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Location: | 15q23 |
Sequence: | 15; NC_000015.10 (71822291..72118577, complement) |
Found to be expressed in testis and placenta, and at lower levels in all the examined tissues with the exception of liver. Isoform 5 was found in leukocytes but not in brain, retina or testis.
Membrane; Single-pass membrane protein. Cytoplasm. Cell junction, synapse. Cell projection, growth cone. Localized in the cytoplasm of cell bodies, dendrites and axons with occasional hints of an enrichment near the plasma membrane. Localized at the neuromuscular junction (By similarity).
PMID: 10409426 by Gorman S.W., et al. The cloning and developmental expression of unconventional myosin IXA (MYO9A) a gene in the Bardet-Biedl syndrome (BBS4) region at chromosome 15q22-q23.
PMID: 9819351 by Chieregatti E., et al. Myr 7 is a novel myosin IX-RhoGAP expressed in rat brain.