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- Table of Contents
Facts about Unconventional myosin-Va.
Also mediates the transport of vesicles into the plasma membrane. May also be required for some polarization process involved in dendrite formation.
Human | |
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Gene Name: | MYO5A |
Uniprot: | Q9Y4I1 |
Entrez: | 4644 |
Belongs to: |
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TRAFAC class myosin-kinesin ATPase superfamily |
Dilute myosin heavy chain, non-muscle; GS1myosin, heavy polypeptide kinase; MYH12myosin-12; MYO5; Myosin heavy chain 12; myosin V; myosin VA (heavy chain 12, myoxin); myosin VA (heavy polypeptide 12, myoxin); Myosin-12; myosin-Va; myoxin; MYR12
Mass (kDA):
215.405 kDA
Human | |
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Location: | 15q21.2 |
Sequence: | 15; NC_000015.10 (52307283..52529050, complement) |
Detected in melanocytes.
PMID: 9207796 by Pastural E., et al. Griscelli disease maps to chromosome 15q21 and is associated with mutations in the myosin-Va gene.
PMID: 8188282 by Engle L.J., et al. Cloning, analysis, and chromosomal localization of myoxin (MYH12), the human homologue to the mouse dilute gene.