Myosin-9 Antibodies

AND MYH9 ELISA kits, Myosin-9 Proteins

Many biological assays use antibodies to detect Myosin-9, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Myosin-9 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Myosin-9 antibodies...

We validate the specificity of these antibodies to Myosin-9 by testing them on tissues known to express MYH9 positively and negatively. Browse below to find the MYH9 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MYH9 Infographic by Boster Bio

All MYH9 Products

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Anti-Myosin-9 MYH9 Antibody

Human, Rat

$405
Cat # A00880
100ul

Anti-Myosin-9 MYH9 Antibody

Human, Mouse, Rat

IP, IHC, WB

$405
Cat # A00880-1
100ul

MYH9 Overview

Facts about Myosin-9.

MYH9 3D structure. Source: alphafold

Myosin-9 (MYH9)

Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. During cell spreading, plays an significant role in cytoskeleton reorganization, focal contacts formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this purpose is automatically antagonized by MYH10.

Gene Information

Human
Gene Name:	MYH9
Uniprot:	P35579
Entrez:	4627

Family

Belongs to:

TRAFAC class myosin-kinesin ATPase superfamily

Alternative Names

Cellular myosin heavy chain, type A; DFNA17; EPSTS; FTNSNMMHC-IIA; MGC104539; MHANMMHC II-a; MYH9 variant protein; Myosin heavy chain 9; Myosin heavy chain, non-muscle IIa; myosin, heavy chain 9, non-muscle; myosin, heavy polypeptide 9, non-muscle; myosin-9; NMHC-II-A; NMMHCA; NMMHC-A; Non-muscle myosin heavy chain A; Non-muscle myosin heavy chain IIa; nonmuscle myosin heavy chain II-A; non-muscle myosin heavy polypeptide 9

Molecular Weight

Mass (kDA):
226.532 kDA

Genomic Context


Human

Location:	22q12.3
Sequence:	22; NC_000022.11 (36281280..36387967, complement)

Tissue Specificity

In the kidney, expressed in the glomeruli. Also expressed in leukocytes.

Subcellular Localizations

Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Colocalizes with actin filaments at lamellipodia margins and at the leading edge of migrating cells (PubMed:20052411). In retinal pigment epithelial cells, predominantly localized to stress fiber-like structures with some localization to cytoplasmic puncta (PubMed:27331610).

Diseases

Kidney Diseases
Kidney Failure, Chronic
Complete Hearing Loss
Sensorineural Hearing Loss (disorder)
Focal Glomerulosclerosis
Glomerulosclerosis (disorder)
Segmental Glomerulosclerosis
Blood Platelet Disorders
Nephritis
Hereditary Nephritis
Hypertensive Disease
Kidney Failure

Hemorrhage
Fechtner Syndrome (disorder)
Proteinuria Of Undiagnosed Cause
Aids-associated Nephropathy
Chronic Kidney Disease
Sebastian Syndrome
Cataract

Interacting Proteins

CXCR4
GRB2
MEN1
NCL
S100A4

Pathways

Pathogenesis
Localization
Glomerular Filtration
Cell Migration
Cytokinesis
Platelet Aggregation
Cell Adhesion
Platelet Formation
Phagocytosis
Cell Death
Hemostasis
Secretion
Cell Division

Cell Motility
Cell-cell Adhesion
Excretion
Muscle Contraction
Lymphocyte Migration
Rna Interference
Transposition

PTMs

Phosphorylation
Glycosylation

Cleavage
Biotinylation

Dephosphorylation

Research Areas

Cell Biology
Cellular Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MYH9

References

PMID: 16106752 by Kato S., et al. Vector-capping: a simple method for preparing a high-quality full- length cDNA library.

PMID: 1912569 by Toothaker L.E., et al. Cellular myosin heavy chain in human leukocytes: isolation of 5' cDNA clones, characterization of the protein, chromosomal localization, and upregulation during myeloid differentiation.